General symptoms and signs
88 codes in this section
About Section R50-R69
Section R50-R69 (R50-R69) covers general symptoms and signs. It sits within the Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified chapter (R00-R99). This section contains 88 ICD-10-CM codes, 68 billable diagnoses you can submit on a claim, and 20 non-billable header codes used to organize the hierarchy.
Codes are organized below by 3-character root. Click the root to see all subcodes underneath it, or click any individual code for full coverage data, payer policies, and linked CPT procedures.
Codes in R50-R69
Grouped by 3-character root code. Click any code for full detail.
| R50.2 | Drug induced fever | Billable |
| R50.8 | Other specified fever | Header |
| R50.81 | Fever presenting with conditions classified elsewhere | Billable |
| R50.82 | Postprocedural fever | Billable |
| R50.83 | Postvaccination fever | Billable |
| R50.84 | Febrile nonhemolytic transfusion reaction | Billable |
| R50.9 | Fever, unspecified | Billable |
| R51.0 | Headache with orthostatic component, not elsewhere classified | Billable |
| R51.9 | Headache, unspecified | Billable |
| R53.0 | Neoplastic (malignant) related fatigue | Billable |
| R53.1 | Weakness | Billable |
| R53.2 | Functional quadriplegia | Billable |
| R53.8 | Other malaise and fatigue | Header |
| R53.81 | Other malaise | Billable |
| R53.82 | Chronic fatigue, unspecified | Billable |
| R53.83 | Other fatigue | Billable |
| R56.0 | Febrile convulsions | Header |
| R56.00 | Simple febrile convulsions | Billable |
| R56.01 | Complex febrile convulsions | Billable |
| R56.1 | Post traumatic seizures | Billable |
| R56.9 | Unspecified convulsions | Billable |
| R57.0 | Cardiogenic shock | Billable |
| R57.1 | Hypovolemic shock | Billable |
| R57.8 | Other shock | Billable |
| R57.9 | Shock, unspecified | Billable |
| R59.0 | Localized enlarged lymph nodes | Billable |
| R59.1 | Generalized enlarged lymph nodes | Billable |
| R59.9 | Enlarged lymph nodes, unspecified | Billable |
| R60.0 | Localized edema | Billable |
| R60.1 | Generalized edema | Billable |
| R60.9 | Edema, unspecified | Billable |
| R62.0 | Delayed milestone in childhood | Billable |
| R62.5 | Other and unspecified lack of expected normal physiological development in childhood | Header |
| R62.50 | Unspecified lack of expected normal physiological development in childhood | Billable |
| R62.51 | Failure to thrive (child) | Billable |
| R62.52 | Short stature (child) | Billable |
| R62.59 | Other lack of expected normal physiological development in childhood | Billable |
| R62.7 | Adult failure to thrive | Billable |
| R63.0 | Anorexia | Billable |
| R63.1 | Polydipsia | Billable |
| R63.2 | Polyphagia | Billable |
| R63.3 | Feeding difficulties | Header |
| R63.30 | Feeding difficulties, unspecified | Billable |
| R63.31 | Pediatric feeding disorder, acute | Billable |
| R63.32 | Pediatric feeding disorder, chronic | Billable |
| R63.39 | Other feeding difficulties | Billable |
| R63.4 | Abnormal weight loss | Billable |
| R63.5 | Abnormal weight gain | Billable |
| R63.6 | Underweight | Billable |
| R63.8 | Other symptoms and signs concerning food and fluid intake | Billable |
| R65.1 | Systemic inflammatory response syndrome (SIRS) of non-infectious origin | Header |
| R65.10 | Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction | Billable |
| R65.11 | Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction | Billable |
| R65.2 | Severe sepsis | Header |
| R65.20 | Severe sepsis without septic shock | Billable |
| R65.21 | Severe sepsis with septic shock | Billable |
| R68.0 | Hypothermia, not associated with low environmental temperature | Billable |
| R68.1 | Nonspecific symptoms peculiar to infancy | Header |
| R68.11 | Excessive crying of infant (baby) | Billable |
| R68.12 | Fussy infant (baby) | Billable |
| R68.13 | Apparent life threatening event in infant (ALTE) | Billable |
| R68.19 | Other nonspecific symptoms peculiar to infancy | Billable |
| R68.2 | Dry mouth, unspecified | Billable |
| R68.3 | Clubbing of fingers | Billable |
| R68.8 | Other general symptoms and signs | Header |
| R68.81 | Early satiety | Billable |
| R68.82 | Decreased libido | Billable |
| R68.83 | Chills (without fever) | Billable |
| R68.84 | Jaw pain | Billable |
| R68.89 | Other general symptoms and signs | Billable |
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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