ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 R65.20

Billable / Specific HCC v28: 2 MCC

Severe sepsis without septic shock

R65
Block
1
Synonyms
600
LCDs
10
Payer Policies
0
Linked CPTs

About ICD-10-CM R65.20

ICD-10-CM code R65.20 represents Severe sepsis without septic shock. This is a billable/specific code in the Symptoms, Signs, and Abnormal Findings chapter (block R65). The 2026 edition of ICD-10-CM R65.20 became effective on October 1, 2025.

Coding Tips for R65.20

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

R65.20 is a CMS-HCC v28 risk-adjustment code (category 2). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: MCC

R65.20 is designated MCC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-MCC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag MCC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under R65.20. Per CMS ICD-10-CM Tabular 2026.

  • Severe sepsis NOS

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 2
ESRD-HCC
Category 2
RxHCC (Part D)
Category 2

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, MCC

codes Severe sepsis without septic shock. As a Major Complication/Comorbidity (MCC), this can shift the DRG assignment to a higher-weighted category, substantial reimbursement impact.

Medicare LCD Coverage for R65.20

Local Coverage Determinations (LCDs) from CMS MACs that list R65.20 as a covered diagnosis.

600 LCDs

Showing top 10 of 600 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93320 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93313 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93312 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 76376 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93318 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93317 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 76377 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT C8927 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT C8925 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93314 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing R65.20.

10 policies

1 Cigna

Transthoracic Echocardiography in Adults - (0510)
Policy ID: MM_0510

5 Medicare

Billing and Coding: Transesophageal Echocardiography (TEE)
Policy ID: ART-52868
Billing and Coding: Transesophageal Echocardiography (TEE)
Policy ID: ART-56809
Billing and Coding: Electrocardiograms
Policy ID: ART-57326
Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Policy ID: ART-58710
Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Policy ID: ART-58720

CPT Codes Commonly Billed with R65.20

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for R65.20

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert R65.20 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
R65.20 99592 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 R65.20, Billing FAQ

Is ICD-10 code R65.20 billable? +

Yes, R65.20 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to R65.20? +

ICD-10 R65.20 includes: Severe sepsis NOS.

Does R65.20 affect Medicare Advantage HCC risk adjustment? +

Yes. R65.20 maps to CMS-HCC v28 category 2. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is R65.20 a CC or MCC for inpatient DRG? +

Yes, this code is designated as MCC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What ICD-9 codes does R65.20 map to? +

Per CMS GEMs, R65.20 maps to ICD-9 codes: 99592. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on June 1, 2026.

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