Malignant neoplasms of mesothelial and soft tissue
63 codes in this section
About Section C45-C49
Section C45-C49 (C45-C49) covers malignant neoplasms of mesothelial and soft tissue. It sits within the Neoplasms chapter (C00-D49). This section contains 63 ICD-10-CM codes, 52 billable diagnoses you can submit on a claim, and 11 non-billable header codes used to organize the hierarchy.
Codes are organized below by 3-character root. Click the root to see all subcodes underneath it, or click any individual code for full coverage data, payer policies, and linked CPT procedures.
Codes in C45-C49
Grouped by 3-character root code. Click any code for full detail.
| C45.0 | Mesothelioma of pleura | Billable |
| C45.1 | Mesothelioma of peritoneum | Billable |
| C45.2 | Mesothelioma of pericardium | Billable |
| C45.7 | Mesothelioma of other sites | Billable |
| C45.9 | Mesothelioma, unspecified | Billable |
| C46.0 | Kaposi's sarcoma of skin | Billable |
| C46.1 | Kaposi's sarcoma of soft tissue | Billable |
| C46.2 | Kaposi's sarcoma of palate | Billable |
| C46.3 | Kaposi's sarcoma of lymph nodes | Billable |
| C46.4 | Kaposi's sarcoma of gastrointestinal sites | Billable |
| C46.5 | Kaposi's sarcoma of lung | Header |
| C46.50 | Kaposi's sarcoma of unspecified lung | Billable |
| C46.51 | Kaposi's sarcoma of right lung | Billable |
| C46.52 | Kaposi's sarcoma of left lung | Billable |
| C46.7 | Kaposi's sarcoma of other sites | Billable |
| C46.9 | Kaposi's sarcoma, unspecified | Billable |
| C47.0 | Malignant neoplasm of peripheral nerves of head, face and neck | Billable |
| C47.1 | Malignant neoplasm of peripheral nerves of upper limb, including shoulder | Header |
| C47.10 | Malignant neoplasm of peripheral nerves of unspecified upper limb, including shoulder | Billable |
| C47.11 | Malignant neoplasm of peripheral nerves of right upper limb, including shoulder | Billable |
| C47.12 | Malignant neoplasm of peripheral nerves of left upper limb, including shoulder | Billable |
| C47.2 | Malignant neoplasm of peripheral nerves of lower limb, including hip | Header |
| C47.20 | Malignant neoplasm of peripheral nerves of unspecified lower limb, including hip | Billable |
| C47.21 | Malignant neoplasm of peripheral nerves of right lower limb, including hip | Billable |
| C47.22 | Malignant neoplasm of peripheral nerves of left lower limb, including hip | Billable |
| C47.3 | Malignant neoplasm of peripheral nerves of thorax | Billable |
| C47.4 | Malignant neoplasm of peripheral nerves of abdomen | Billable |
| C47.5 | Malignant neoplasm of peripheral nerves of pelvis | Billable |
| C47.6 | Malignant neoplasm of peripheral nerves of trunk, unspecified | Billable |
| C47.8 | Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system | Billable |
| C47.9 | Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified | Billable |
| C48.0 | Malignant neoplasm of retroperitoneum | Billable |
| C48.1 | Malignant neoplasm of specified parts of peritoneum | Billable |
| C48.2 | Malignant neoplasm of peritoneum, unspecified | Billable |
| C48.8 | Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum | Billable |
| C49.0 | Malignant neoplasm of connective and soft tissue of head, face and neck | Billable |
| C49.1 | Malignant neoplasm of connective and soft tissue of upper limb, including shoulder | Header |
| C49.10 | Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder | Billable |
| C49.11 | Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder | Billable |
| C49.12 | Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder | Billable |
| C49.2 | Malignant neoplasm of connective and soft tissue of lower limb, including hip | Header |
| C49.20 | Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip | Billable |
| C49.21 | Malignant neoplasm of connective and soft tissue of right lower limb, including hip | Billable |
| C49.22 | Malignant neoplasm of connective and soft tissue of left lower limb, including hip | Billable |
| C49.3 | Malignant neoplasm of connective and soft tissue of thorax | Billable |
| C49.4 | Malignant neoplasm of connective and soft tissue of abdomen | Billable |
| C49.5 | Malignant neoplasm of connective and soft tissue of pelvis | Billable |
| C49.6 | Malignant neoplasm of connective and soft tissue of trunk, unspecified | Billable |
| C49.8 | Malignant neoplasm of overlapping sites of connective and soft tissue | Billable |
| C49.9 | Malignant neoplasm of connective and soft tissue, unspecified | Billable |
| C49.A | Gastrointestinal stromal tumor | Header |
| C49.A0 | Gastrointestinal stromal tumor, unspecified site | Billable |
| C49.A1 | Gastrointestinal stromal tumor of esophagus | Billable |
| C49.A2 | Gastrointestinal stromal tumor of stomach | Billable |
| C49.A3 | Gastrointestinal stromal tumor of small intestine | Billable |
| C49.A4 | Gastrointestinal stromal tumor of large intestine | Billable |
| C49.A5 | Gastrointestinal stromal tumor of rectum | Billable |
| C49.A9 | Gastrointestinal stromal tumor of other sites | Billable |
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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