ICD-10 C48
Non-Billable HeaderMalignant neoplasm of retroperitoneum and peritoneum
About ICD-10-CM C48
ICD-10-CM code C48 represents Malignant neoplasm of retroperitoneum and peritoneum. This is a non-billable header code in the Neoplasms chapter (block C48). The 2026 edition of ICD-10-CM C48 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Type 1 Excludes
Pure excludes, these codes can never be coded together with C48. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- Kaposi's sarcoma of connective tissue (C46.1)
- mesothelioma (C45.-)
Medicare LCD Coverage for C48
Local Coverage Determinations (LCDs) from CMS MACs that list C48 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing C48.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but C48 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with C48
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To C48
Other codes in section C45-C49 (Malignant neoplasms of mesothelial and soft tissue).
ICD-10 C48, Billing FAQ
Is ICD-10 code C48 billable? +
No, C48 is a non-billable header code. Use a more specific child code from block C48 when submitting claims.
What codes are Type 1 Excludes for C48? +
Type 1 Excludes (never code together with C48): Kaposi's sarcoma of connective tissue (C46.1); mesothelioma (C45.-)
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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