ICD-10 D89.833
Billable / Specific CCCytokine release syndrome, grade 3
About ICD-10-CM D89.833
ICD-10-CM code D89.833 represents Cytokine release syndrome, grade 3. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D89). The 2026 edition of ICD-10-CM D89.833 became effective on October 1, 2025.
Coding Tips for D89.833
Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.
D89.833 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.
Inpatient DRG Impact, CC
Excl Cytokine release syndrome, grade 3. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.
Medicare LCD Coverage for D89.833
Local Coverage Determinations (LCDs) from CMS MACs that list D89.833 as a covered diagnosis.
Showing top 10 of 56 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing D89.833.
5 Medicare
CPT Codes Commonly Billed with D89.833
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To D89.833
Other codes in section D80-D89 (Certain disorders involving the immune mechanism).
ICD-10 D89.833, Billing FAQ
Is ICD-10 code D89.833 billable? +
Yes, D89.833 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
Is D89.833 a CC or MCC for inpatient DRG? +
Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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