ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D89.0

Billable / Specific

Polyclonal hypergammaglobulinemia

D89
Block
2
Synonyms
583
LCDs
11
Payer Policies
6
Linked CPTs

About ICD-10-CM D89.0

ICD-10-CM code D89.0 represents Polyclonal hypergammaglobulinemia. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D89). The 2026 edition of ICD-10-CM D89.0 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D89.0. Per CMS ICD-10-CM Tabular 2026.

  • Benign hypergammaglobulinemic purpura
  • Polyclonal gammopathy NOS

Medicare LCD Coverage for D89.0

Local Coverage Determinations (LCDs) from CMS MACs that list D89.0 as a covered diagnosis.

583 LCDs

Showing top 10 of 583 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Article ID: 56638, Effective: 2025-07-01 00:00:00, 60 covered, 1 non-covered
CPT 87506 →
CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Article ID: 56638, Effective: 2025-07-01 00:00:00, 60 covered, 1 non-covered
CPT 87507 →
CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Article ID: 56638, Effective: 2025-07-01 00:00:00, 60 covered, 1 non-covered
CPT 87505 →
CMS LCD: Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Article ID: 58761, Effective: 2026-03-12 00:00:00, 851 covered, 0 non-covered
CPT 87555 →
CMS LCD: Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Article ID: 58761, Effective: 2026-03-12 00:00:00, 851 covered, 0 non-covered
CPT 87653 →
CMS LCD: Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Article ID: 58761, Effective: 2026-03-12 00:00:00, 851 covered, 0 non-covered
CPT 87486 →
CMS LCD: Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Article ID: 58761, Effective: 2026-03-12 00:00:00, 851 covered, 0 non-covered
CPT 87626 →
CMS LCD: Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Article ID: 58761, Effective: 2026-03-12 00:00:00, 851 covered, 0 non-covered
CPT 0109U →
CMS LCD: Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Article ID: 58761, Effective: 2026-03-12 00:00:00, 851 covered, 0 non-covered
CPT 87516 →
CMS LCD: Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Article ID: 58761, Effective: 2026-03-12 00:00:00, 851 covered, 0 non-covered
CPT 87517 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D89.0.

11 policies

1 Cigna

Flow Cytometry - (0538)
Policy ID: MM_0538

5 Medicare

Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Policy ID: ART-56638
Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Policy ID: ART-56642
Billing and Coding: Respiratory Pathogen Panel Testing
Policy ID: ART-58575
Billing and Coding: Respiratory Pathogen Panel Testing
Policy ID: ART-58577
Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Policy ID: ART-58710

CPT Codes Commonly Billed with D89.0

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

6 linkages
  • 87507 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87505 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87506 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87812 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
  • 87428 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
  • 87913 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD

Convert D89.0 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D89.0 2730 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D89.0, Billing FAQ

Is ICD-10 code D89.0 billable? +

Yes, D89.0 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D89.0? +

ICD-10 D89.0 includes: Benign hypergammaglobulinemic purpura; Polyclonal gammopathy NOS.

What CPT codes are commonly billed with D89.0? +

Procedures frequently paired with D89.0 include: 87507, 87505, 87506, 87812, 87428.

What ICD-9 codes does D89.0 map to? +

Per CMS GEMs, D89.0 maps to ICD-9 codes: 2730. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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