ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D84.822

Billable / Specific HCC v28: 47 CC

Immunodeficiency due to external causes

D84
Block
0
Synonyms
615
LCDs
11
Payer Policies
3
Linked CPTs

About ICD-10-CM D84.822

ICD-10-CM code D84.822 represents Immunodeficiency due to external causes. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D84). The 2026 edition of ICD-10-CM D84.822 became effective on October 1, 2025.

Coding Tips for D84.822

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D84.822 is a CMS-HCC v28 risk-adjustment code (category 47). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: CC

D84.822 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Use Additional Code

When coding D84.822, also report these additional codes when applicable.

  • code for external cause such as:
  • exposure to ionizing radiation (W88)

Coding Notes

Code Also

  • , if applicable, radiological procedure and radiotherapy (Y84.2)

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 47
ESRD-HCC
Category 47
RxHCC (Part D)
Category 47

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, CC

codes Immunodeficiency due to external causes. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for D84.822

Local Coverage Determinations (LCDs) from CMS MACs that list D84.822 as a covered diagnosis.

615 LCDs

Showing top 10 of 615 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Article ID: 56638, Effective: 2025-07-01 00:00:00, 60 covered, 1 non-covered
CPT 87506 →
CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Article ID: 56638, Effective: 2025-07-01 00:00:00, 60 covered, 1 non-covered
CPT 87507 →
CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Article ID: 56638, Effective: 2025-07-01 00:00:00, 60 covered, 1 non-covered
CPT 87505 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 88189 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 86360 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 86361 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 88187 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 86363 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 86359 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 86356 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D84.822.

11 policies

5 Medicare

Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Policy ID: ART-56638
Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Policy ID: ART-56642
Billing and Coding: Removal of Benign Skin Lesions
Policy ID: ART-57044
Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-57689

1 Aetna

Herpes Simplex Virus - Screening and Diagnosis
Policy ID: CPB-0433

CPT Codes Commonly Billed with D84.822

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

3 linkages
  • 87507 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87505 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87506 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD

ICD-10 D84.822, Billing FAQ

Is ICD-10 code D84.822 billable? +

Yes, D84.822 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does D84.822 affect Medicare Advantage HCC risk adjustment? +

Yes. D84.822 maps to CMS-HCC v28 category 47. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is D84.822 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with D84.822? +

Procedures frequently paired with D84.822 include: 87507, 87505, 87506.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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