ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D84.1

Billable / Specific HCC v28: 23

Defects in the complement system

D84
Block
1
Synonyms
677
LCDs
18
Payer Policies
6
Linked CPTs

About ICD-10-CM D84.1

ICD-10-CM code D84.1 represents Defects in the complement system. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D84). The 2026 edition of ICD-10-CM D84.1 became effective on October 1, 2025.

Coding Tips for D84.1

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D84.1 is a CMS-HCC v28 risk-adjustment code (category 23). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D84.1. Per CMS ICD-10-CM Tabular 2026.

  • C1 esterase inhibitor [C1-INH] deficiency

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 23
ESRD-HCC
Category 23
RxHCC (Part D)
Category 23

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for D84.1

Local Coverage Determinations (LCDs) from CMS MACs that list D84.1 as a covered diagnosis.

677 LCDs

Showing top 10 of 677 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94660 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94726 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94664 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94618 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94772 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94642 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT G0238 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94004 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94668 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94680 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D84.1.

18 policies

5 Medicare

Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-55717
Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Policy ID: ART-56638
Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Policy ID: ART-56642
Billing and Coding: Intravenous Immunoglobulin (IVIG)
Policy ID: ART-56718

2 Aetna

Meningococcal Vaccines
Policy ID: CPB-0356
Hereditary Angioedema
Policy ID: CPB-0782

CPT Codes Commonly Billed with D84.1

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

6 linkages
  • 87507 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87505 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87506 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87812 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
  • 87428 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
  • 87913 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD

Convert D84.1 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D84.1 2776 10000
D84.1 2798 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D84.1, Billing FAQ

Is ICD-10 code D84.1 billable? +

Yes, D84.1 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D84.1? +

ICD-10 D84.1 includes: C1 esterase inhibitor [C1-INH] deficiency.

Does D84.1 affect Medicare Advantage HCC risk adjustment? +

Yes. D84.1 maps to CMS-HCC v28 category 23. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What CPT codes are commonly billed with D84.1? +

Procedures frequently paired with D84.1 include: 87507, 87505, 87506, 87812, 87428.

What ICD-9 codes does D84.1 map to? +

Per CMS GEMs, D84.1 maps to ICD-9 codes: 2776, 2798. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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