ICD-10 D81.818
Billable / SpecificOther biotin-dependent carboxylase deficiency
About ICD-10-CM D81.818
ICD-10-CM code D81.818 represents Other biotin-dependent carboxylase deficiency. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D81). The 2026 edition of ICD-10-CM D81.818 became effective on October 1, 2025.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under D81.818. Per CMS ICD-10-CM Tabular 2026.
- Holocarboxylase synthetase deficiency
- Other multiple carboxylase deficiency
Medicare LCD Coverage for D81.818
Local Coverage Determinations (LCDs) from CMS MACs that list D81.818 as a covered diagnosis.
Showing top 10 of 623 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing D81.818.
1 Cigna
5 Medicare
1 Aetna
CPT Codes Commonly Billed with D81.818
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- 87507 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
- 87505 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
- 87506 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
- 11719 CMS LCD: Billing and Coding: Routine Foot Care and Debridement of Nails CMS LCD
- G0127 CMS LCD: Billing and Coding: Routine Foot Care and Debridement of Nails CMS LCD
- 11056 CMS LCD: Billing and Coding: Routine Foot Care and Debridement of Nails CMS LCD
- 87812 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
- 87428 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
- 87913 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
- J3420 CMS LCD: Billing and Coding: Vitamin B<sub>12</sub> Injections CMS LCD
Convert D81.818 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| D81.818 | 2662 | 10000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To D81.818
Other codes in section D80-D89 (Certain disorders involving the immune mechanism).
ICD-10 D81.818, Billing FAQ
Is ICD-10 code D81.818 billable? +
Yes, D81.818 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to D81.818? +
ICD-10 D81.818 includes: Holocarboxylase synthetase deficiency; Other multiple carboxylase deficiency.
What CPT codes are commonly billed with D81.818? +
Procedures frequently paired with D81.818 include: 87507, 87505, 87506, 11719, G0127.
What ICD-9 codes does D81.818 map to? +
Per CMS GEMs, D81.818 maps to ICD-9 codes: 2662. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on July 16, 2026.
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