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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D81.810

Billable / Specific

Biotinidase deficiency

D81
Block
0
Synonyms
623
LCDs
13
Payer Policies
6
Linked CPTs

About ICD-10-CM D81.810

ICD-10-CM code D81.810 represents Biotinidase deficiency. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D81). The 2026 edition of ICD-10-CM D81.810 became effective on October 1, 2025.

Medicare LCD Coverage for D81.810

Local Coverage Determinations (LCDs) from CMS MACs that list D81.810 as a covered diagnosis.

623 LCDs

Showing top 10 of 623 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94660 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94726 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94664 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94618 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94772 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94642 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT G0238 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94004 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94668 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94680 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D81.810.

13 policies

1 Cigna

Infant Nutritional Formula - (0136)
Policy ID: MM_0136

5 Medicare

Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Policy ID: ART-56638
Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
Policy ID: ART-56642
Billing and Coding: Oximetry Services
Policy ID: ART-57205
Billing and Coding: Respiratory Care
Policy ID: ART-57224
Billing and Coding: Respiratory Pathogen Panel Testing
Policy ID: ART-58575

CPT Codes Commonly Billed with D81.810

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

6 linkages
  • 87507 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87505 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87506 CMS LCD: Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs) CMS LCD
  • 87812 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
  • 87428 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD
  • 87913 CMS LCD: Billing and Coding: Respiratory Pathogen Panel Testing CMS LCD

Convert D81.810 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D81.810 2776 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D81.810, Billing FAQ

Is ICD-10 code D81.810 billable? +

Yes, D81.810 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What CPT codes are commonly billed with D81.810? +

Procedures frequently paired with D81.810 include: 87507, 87505, 87506, 87812, 87428.

What ICD-9 codes does D81.810 map to? +

Per CMS GEMs, D81.810 maps to ICD-9 codes: 2776. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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