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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D58.9

Billable / Specific HCC v28: 48 CC

Hereditary hemolytic anemia, unspecified

D58
Block
0
Synonyms
153
LCDs
7
Payer Policies
0
Linked CPTs

About ICD-10-CM D58.9

ICD-10-CM code D58.9 represents Hereditary hemolytic anemia, unspecified. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D58). The 2026 edition of ICD-10-CM D58.9 became effective on October 1, 2025.

Coding Tips for D58.9

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D58.9 is a CMS-HCC v28 risk-adjustment code (category 48). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: CC

D58.9 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 48
ESRD-HCC
Category 48
RxHCC (Part D)
Category 48

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, CC

codes Hereditary hemolytic anemia, unspecified. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for D58.9

Local Coverage Determinations (LCDs) from CMS MACs that list D58.9 as a covered diagnosis.

153 LCDs

Showing top 10 of 153 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0198U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81109 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0197U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0183U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81107 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0186U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81106 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0184U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0221U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0200U →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D58.9.

7 policies

1 Cigna

Flow Cytometry - (0538)
Policy ID: MM_0538

5 Medicare

Billing and Coding: Intravenous Immunoglobulin (IVIG)
Policy ID: ART-56718
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57110
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57124
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57155
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-58308

1 Aetna

Autotransfusers and Red Blood Cell Genotyping
Policy ID: CPB-0639

CPT Codes Commonly Billed with D58.9

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for D58.9

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert D58.9 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D58.9 2829 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D58.9, Billing FAQ

Is ICD-10 code D58.9 billable? +

Yes, D58.9 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does D58.9 affect Medicare Advantage HCC risk adjustment? +

Yes. D58.9 maps to CMS-HCC v28 category 48. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is D58.9 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What ICD-9 codes does D58.9 map to? +

Per CMS GEMs, D58.9 maps to ICD-9 codes: 2829. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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