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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D55.9

Billable / Specific HCC v28: 48

Anemia due to enzyme disorder, unspecified

D55
Block
0
Synonyms
153
LCDs
5
Payer Policies
2
Linked CPTs

About ICD-10-CM D55.9

ICD-10-CM code D55.9 represents Anemia due to enzyme disorder, unspecified. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D55). The 2026 edition of ICD-10-CM D55.9 became effective on October 1, 2025.

Coding Tips for D55.9

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D55.9 is a CMS-HCC v28 risk-adjustment code (category 48). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 48
ESRD-HCC
Category 48
RxHCC (Part D)
Category 48

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for D55.9

Local Coverage Determinations (LCDs) from CMS MACs that list D55.9 as a covered diagnosis.

153 LCDs

Showing top 10 of 153 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0198U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81109 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0197U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0183U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81107 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0186U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81106 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0184U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0221U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0200U →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D55.9.

5 policies

5 Medicare

Billing and Coding: Intravenous Immunoglobulin (IVIG)
Policy ID: ART-56718
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57110
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57124
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57155
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-58308

CPT Codes Commonly Billed with D55.9

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • J2791 CMS LCD: Billing and Coding: Intravenous Immunoglobulin (IVIG) CMS LCD
  • J2792 CMS LCD: Billing and Coding: Intravenous Immunoglobulin (IVIG) CMS LCD

Convert D55.9 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D55.9 2823 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D55.9, Billing FAQ

Is ICD-10 code D55.9 billable? +

Yes, D55.9 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does D55.9 affect Medicare Advantage HCC risk adjustment? +

Yes. D55.9 maps to CMS-HCC v28 category 48. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What CPT codes are commonly billed with D55.9? +

Procedures frequently paired with D55.9 include: J2791, J2792.

What ICD-9 codes does D55.9 map to? +

Per CMS GEMs, D55.9 maps to ICD-9 codes: 2823. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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