PAYER READY CREDENTIALING & COMPLIANCE
ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D56.9

Billable / Specific

Thalassemia, unspecified

D56
Block
1
Synonyms
206
LCDs
14
Payer Policies
2
Linked CPTs

About ICD-10-CM D56.9

ICD-10-CM code D56.9 represents Thalassemia, unspecified. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D56). The 2026 edition of ICD-10-CM D56.9 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D56.9. Per CMS ICD-10-CM Tabular 2026.

  • Mediterranean anemia (with other hemoglobinopathy)

Medicare LCD Coverage for D56.9

Local Coverage Determinations (LCDs) from CMS MACs that list D56.9 as a covered diagnosis.

206 LCDs

Showing top 10 of 206 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0198U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81109 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0197U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0183U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81107 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0186U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81106 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0184U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0221U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0200U →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D56.9.

14 policies

3 Aetna

Oxygen - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0002
Chelation Therapy
Policy ID: CPB-0234
Autotransfusers and Red Blood Cell Genotyping
Policy ID: CPB-0639

2 Cigna

Flow Cytometry - (0538)
Policy ID: MM_0538
Transthoracic Echocardiography in Children - (0523)
Policy ID: MM_0523

5 Medicare

Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-55717
Billing and Coding: Computerized Axial Tomography (CT), Thorax
Policy ID: ART-56580
Billing and Coding: Non-Invasive Vascular Studies
Policy ID: ART-56697
Billing and Coding: Intravenous Immunoglobulin (IVIG)
Policy ID: ART-56718
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57110

CPT Codes Commonly Billed with D56.9

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • J2791 CMS LCD: Billing and Coding: Intravenous Immunoglobulin (IVIG) CMS LCD
  • J2792 CMS LCD: Billing and Coding: Intravenous Immunoglobulin (IVIG) CMS LCD

Convert D56.9 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D56.9 28240 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D56.9, Billing FAQ

Is ICD-10 code D56.9 billable? +

Yes, D56.9 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D56.9? +

ICD-10 D56.9 includes: Mediterranean anemia (with other hemoglobinopathy).

What CPT codes are commonly billed with D56.9? +

Procedures frequently paired with D56.9 include: J2791, J2792.

What ICD-9 codes does D56.9 map to? +

Per CMS GEMs, D56.9 maps to ICD-9 codes: 28240. Useful for legacy data review and historical claim analysis.

Get the full PayerReady toolkit

Free access to CPT/ICD-10 lookup, denial appeals, fee comparator, and claim auditing with credentialing enrollment.

Start free →

Run this code through our claim audit tool

Check NCCI bundling, MUE limits, and modifier logic before submission.

Try the auditor →

Did this page help?

Quick signal so we know what to improve.

Thanks!

If you want a code reference page that doesn't exist yet, email coding@payerready.com.

Sorry to hear that.

Tell us what's missing or wrong: coding@payerready.com. We respond within 5 business days.

Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

Powered by 11K CPT · 98K ICD-10 · 860K MPFS rates · 4.5M NCCI edits · 9.5M NPIs. Our data methodology · About our coding team

Every month un-credentialed is revenue you never bill

Sign up free, add your first provider, and watch the pipeline start moving this week.

Ask CredBrain

Answers from your credentialing team's verified knowledge base

Hi, I'm CredBrain. I answer from your credentialing team's verified knowledge base: payer join paths, state rules, timelines, associate billing, and enrollment workflows. If I don't have a verified answer, I'll say so and point you to your team. What would you like to know?

Try asking