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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D53.9

Billable / Specific

Nutritional anemia, unspecified

D53
Block
1
Synonyms
165
LCDs
10
Payer Policies
2
Linked CPTs

About ICD-10-CM D53.9

ICD-10-CM code D53.9 represents Nutritional anemia, unspecified. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D53). The 2026 edition of ICD-10-CM D53.9 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D53.9. Per CMS ICD-10-CM Tabular 2026.

  • Simple chronic anemia

Type 1 Excludes

Pure excludes, these codes can never be coded together with D53.9. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • anemia NOS (D64.9)

Medicare LCD Coverage for D53.9

Local Coverage Determinations (LCDs) from CMS MACs that list D53.9 as a covered diagnosis.

165 LCDs

Showing top 10 of 165 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0198U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81109 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0197U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0183U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81107 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0186U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81106 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0184U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0221U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0200U →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D53.9.

10 policies

2 Cigna

Flow Cytometry - (0538)
Policy ID: MM_0538
Serum Folate and Red Blood Cell Folate Testing - (0567)
Policy ID: MM_0567

5 Medicare

Billing and Coding: Assays for Vitamins and Metabolic Function
Policy ID: ART-56416
Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57110
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57124
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57155

1 Aetna

Vitamin B-12 Therapy
Policy ID: CPB-0536

CPT Codes Commonly Billed with D53.9

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • J3420 CMS LCD: Billing and Coding: Vitamin B<sub>12</sub> Injections CMS LCD
  • J3425 CMS LCD: Billing and Coding: Vitamin B<sub>12</sub> Injections CMS LCD

Convert D53.9 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D53.9 2819 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D53.9, Billing FAQ

Is ICD-10 code D53.9 billable? +

Yes, D53.9 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D53.9? +

ICD-10 D53.9 includes: Simple chronic anemia.

What codes are Type 1 Excludes for D53.9? +

Type 1 Excludes (never code together with D53.9): anemia NOS (D64.9)

What CPT codes are commonly billed with D53.9? +

Procedures frequently paired with D53.9 include: J3420, J3425.

What ICD-9 codes does D53.9 map to? +

Per CMS GEMs, D53.9 maps to ICD-9 codes: 2819. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 18, 2026.

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