ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D50.0

Billable / Specific

Iron deficiency anemia secondary to blood loss (chronic)

D50
Block
1
Synonyms
393
LCDs
20
Payer Policies
32
Linked CPTs

About ICD-10-CM D50.0

ICD-10-CM code D50.0 represents Iron deficiency anemia secondary to blood loss (chronic). This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D50). The 2026 edition of ICD-10-CM D50.0 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D50.0. Per CMS ICD-10-CM Tabular 2026.

  • Posthemorrhagic anemia (chronic)

Type 1 Excludes

Pure excludes, these codes can never be coded together with D50.0. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • acute posthemorrhagic anemia (D62)
  • congenital anemia from fetal blood loss (P61.3)

Medicare LCD Coverage for D50.0

Local Coverage Determinations (LCDs) from CMS MACs that list D50.0 as a covered diagnosis.

393 LCDs

Showing top 10 of 393 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 45398 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 44392 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 45386 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 45378 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 44390 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 45393 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 44394 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 44401 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 44407 →
CMS LCD: Billing and Coding: Diagnostic Colonoscopy
Article ID: 55937, Effective: 2026-02-04 00:00:00, 244 covered, 1 non-covered
CPT 45391 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D50.0.

20 policies

1 Cigna

Flow Cytometry - (0538)
Policy ID: MM_0538

5 Medicare

Billing and Coding: Diagnostic Colonoscopy
Policy ID: ART-55937
Billing and Coding: Upper Gastrointestinal Endoscopy and Visualization
Policy ID: ART-56389
Billing and Coding: Colonoscopy and Sigmoidoscopy-Diagnostic
Policy ID: ART-56394
Billing and Coding: Colonoscopy/Sigmoidoscopy/Proctosigmoidoscopy
Policy ID: ART-56456
Billing and Coding: Endoscopy by Capsule
Policy ID: ART-56461

5 Aetna

Hyperbaric Oxygen Therapy (HBOT)
Policy ID: CPB-0172
Colonoscopy, Colorectal Cancer Screening, and Related Procedures
Policy ID: CPB-0516
Lead Testing
Policy ID: CPB-0553
Capsule Endoscopy
Policy ID: CPB-0588
Double Balloon Enteroscopy
Policy ID: CPB-0737

CPT Codes Commonly Billed with D50.0

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

32 linkages
  • 43235 Diagnostic EGD — abdominal pain, nausea, vomiting, GERD, gastric ulcer, gastritis, hematemesis, melena, Barrett esophagus, dysphagia, esophagitis, weight loss, iron deficiency anemia, polyp Gastroenterology
  • 45378 Diagnostic colonoscopy — colorectal screening, family hx colon cancer, polyp, melena, iron def anemia, diverticulosis, ulcerative colitis, Crohn, occult blood, rectal polyp, weight loss, IBS Gastroenterology
  • 45380 Colonoscopy with biopsy — colon polyp, neoplasm of colon, melena, iron deficiency anemia, screening, personal hx polyps, UC, occult blood Gastroenterology
  • 45381 Colonoscopy with directed submucosal injection — polyp removal facilitation, same dx as polypectomy Gastroenterology
  • 85025 CBC with differential — anemia, iron deficiency, fatigue, thrombocytopenia, neutropenia, leukemia, lymphoma, abnormal labs, routine exam, screening, fever, elevated WBC Laboratory
  • 44408 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 45379 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 44406 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 45390 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 45392 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD

Convert D50.0 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D50.0 2800 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D50.0, Billing FAQ

Is ICD-10 code D50.0 billable? +

Yes, D50.0 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D50.0? +

ICD-10 D50.0 includes: Posthemorrhagic anemia (chronic).

What codes are Type 1 Excludes for D50.0? +

Type 1 Excludes (never code together with D50.0): acute posthemorrhagic anemia (D62); congenital anemia from fetal blood loss (P61.3)

What CPT codes are commonly billed with D50.0? +

Procedures frequently paired with D50.0 include: 43235, 45378, 45380, 45381, 85025.

What ICD-9 codes does D50.0 map to? +

Per CMS GEMs, D50.0 maps to ICD-9 codes: 2800. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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