ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D49.7

Billable / Specific

Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system

D49
Block
0
Synonyms
245
LCDs
22
Payer Policies
1
Linked CPTs

About ICD-10-CM D49.7

ICD-10-CM code D49.7 represents Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system. This is a billable/specific code in the Neoplasms chapter (block D49). The 2026 edition of ICD-10-CM D49.7 became effective on October 1, 2025.

Type 1 Excludes

Pure excludes, these codes can never be coded together with D49.7. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • neoplasm of unspecified behavior of peripheral, sympathetic, and parasympathetic nerves and ganglia (D49.2)

Medicare LCD Coverage for D49.7

Local Coverage Determinations (LCDs) from CMS MACs that list D49.7 as a covered diagnosis.

245 LCDs

Showing top 10 of 245 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77402 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77371 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 61797 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT G0339 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77338 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77432 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 61800 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77372 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77435 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77407 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D49.7.

22 policies

1 Aetna

Positron Emission Tomography (PET) - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0071

5 Medicare

Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
Policy ID: ART-52480
Billing and Coding: Biomarkers for Oncology
Policy ID: ART-52986
Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID� Update
Policy ID: ART-53101
Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID�
Policy ID: ART-54188
Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID� Update
Policy ID: ART-54386

CPT Codes Commonly Billed with D49.7

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

1 linkages
  • 76536 CMS LCD: Billing and Coding: Ultrasound, Soft Tissues of Head and Neck CMS LCD

Convert D49.7 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D49.7 2397 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D49.7, Billing FAQ

Is ICD-10 code D49.7 billable? +

Yes, D49.7 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What codes are Type 1 Excludes for D49.7? +

Type 1 Excludes (never code together with D49.7): neoplasm of unspecified behavior of peripheral, sympathetic, and parasympathetic nerves and ganglia (D49.2)

What CPT codes are commonly billed with D49.7? +

Procedures frequently paired with D49.7 include: 76536.

What ICD-9 codes does D49.7 map to? +

Per CMS GEMs, D49.7 maps to ICD-9 codes: 2397. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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