ICD-10 D49.0
Billable / SpecificNeoplasm of unspecified behavior of digestive system
About ICD-10-CM D49.0
ICD-10-CM code D49.0 represents Neoplasm of unspecified behavior of digestive system. This is a billable/specific code in the Neoplasms chapter (block D49). The 2026 edition of ICD-10-CM D49.0 became effective on October 1, 2025.
Type 1 Excludes
Pure excludes, these codes can never be coded together with D49.0. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- neoplasm of unspecified behavior of margin of anus (D49.2)
- neoplasm of unspecified behavior of perianal skin (D49.2)
- neoplasm of unspecified behavior of skin of anus (D49.2)
Medicare LCD Coverage for D49.0
Local Coverage Determinations (LCDs) from CMS MACs that list D49.0 as a covered diagnosis.
Showing top 10 of 552 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing D49.0.
1 Cigna
5 Medicare
CPT Codes Commonly Billed with D49.0
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- 44408 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 45379 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 44406 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 45390 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 45392 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 44394 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 44402 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 44390 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 44405 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
- 44388 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
Convert D49.0 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| D49.0 | 2390 | 00000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To D49.0
Other codes in section D49 (Neoplasms of unspecified behavior).
ICD-10 D49.0, Billing FAQ
Is ICD-10 code D49.0 billable? +
Yes, D49.0 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What codes are Type 1 Excludes for D49.0? +
Type 1 Excludes (never code together with D49.0): neoplasm of unspecified behavior of margin of anus (D49.2); neoplasm of unspecified behavior of perianal skin (D49.2); neoplasm of unspecified behavior of skin of anus (D49.2)
What CPT codes are commonly billed with D49.0? +
Procedures frequently paired with D49.0 include: 44408, 45379, 44406, 45390, 45392.
What ICD-9 codes does D49.0 map to? +
Per CMS GEMs, D49.0 maps to ICD-9 codes: 2390. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on July 16, 2026.
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