ICD-10 N16
Billable / SpecificRenal tubulo-interstitial disorders in diseases classified elsewhere
About ICD-10-CM N16
ICD-10-CM code N16 represents Renal tubulo-interstitial disorders in diseases classified elsewhere. This is a billable/specific code in the Genitourinary System chapter (block N16). The 2026 edition of ICD-10-CM N16 became effective on October 1, 2025.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under N16. Per CMS ICD-10-CM Tabular 2026.
- Pyelonephritis
- Tubulo-interstitial nephritis
Type 1 Excludes
Pure excludes, these codes can never be coded together with N16. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
- pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
- pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
- pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
- pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)
- pyelonephritis and tubulo-interstitial nephritis in Sjogren syndrome (M35.04)
- pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (M32.15)
- pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (B58.83)
- renal tubular degeneration in diabetes (E08-E13 with .29)
- syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)
Coding Notes
Code First
- underlying disease, such as:
- brucellosis (A23.0-A23.9)
- cryoglobulinemia (D89.1)
- glycogen storage disease (E74.0-)
- leukemia (C91-C95)
- lymphoma (C81.0-C85.9, C96.0-C96.9)
- multiple myeloma (C90.0-)
- sepsis (A40.0-A41.9)
- Wilson's disease (E83.01)
Medicare LCD Coverage for N16
Local Coverage Determinations (LCDs) from CMS MACs that list N16 as a covered diagnosis.
Showing top 10 of 19 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing N16.
4 Medicare
CPT Codes Commonly Billed with N16
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Convert N16 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| N16 | 58381 | 10000 |
| N16 | 59081 | 10000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To N16
Other codes in section N10-N16 (Renal tubulo-interstitial diseases).
ICD-10 N16, Billing FAQ
Is ICD-10 code N16 billable? +
Yes, N16 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to N16? +
ICD-10 N16 includes: Pyelonephritis; Tubulo-interstitial nephritis.
What codes are Type 1 Excludes for N16? +
Type 1 Excludes (never code together with N16): diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84); pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49); pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
What ICD-9 codes does N16 map to? +
Per CMS GEMs, N16 maps to ICD-9 codes: 58381, 59081. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
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