ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 N10

Billable / Specific CC

Acute pyelonephritis

N10
Block
5
Synonyms
12
LCDs
2
Payer Policies
2
Linked CPTs

About ICD-10-CM N10

ICD-10-CM code N10 represents Acute pyelonephritis. This is a billable/specific code in the Genitourinary System chapter (block N10). The 2026 edition of ICD-10-CM N10 became effective on October 1, 2025.

Coding Tips for N10

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Inpatient DRG impact: CC

N10 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under N10. Per CMS ICD-10-CM Tabular 2026.

  • Acute infectious interstitial nephritis
  • Acute pyelitis
  • Acute tubulo-interstitial nephritis
  • Hemoglobin nephrosis
  • Myoglobin nephrosis

Use Additional Code

When coding N10, also report these additional codes when applicable.

  • code (B95-B97), to identify infectious agent.

Inpatient DRG Impact, CC

1325:279 codes Acute pyelonephritis. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for N10

Local Coverage Determinations (LCDs) from CMS MACs that list N10 as a covered diagnosis.

12 LCDs

Showing top 10 of 12 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74170 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74177 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74160 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74178 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74150 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72194 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74176 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72192 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72193 →
CMS LCD: Billing and Coding: Retroperitoneal Ultrasound
Article ID: 55336, Effective: 2025-10-01 00:00:00, 797 covered, 0 non-covered
CPT 76775 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing N10.

2 policies

2 Medicare

Billing and Coding: Retroperitoneal Ultrasound
Policy ID: ART-55336
Billing and Coding: CT of the Abdomen and Pelvis
Policy ID: ART-56421

CPT Codes Commonly Billed with N10

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • 81001 Urinalysis with microscopy — UTI, cystitis, dysuria, urinary frequency, abnormal urine, pyelonephritis, chronic pyelonephritis, fever, kidney stone Laboratory
  • 87086 Urine culture — UTI, cystitis, pyelonephritis, abnormal urine, dysuria Laboratory

Convert N10 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
N10 59010 10000
N10 59011 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 N10, Billing FAQ

Is ICD-10 code N10 billable? +

Yes, N10 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to N10? +

ICD-10 N10 includes: Acute infectious interstitial nephritis; Acute pyelitis; Acute tubulo-interstitial nephritis, and 2 more clinical synonyms.

Is N10 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with N10? +

Procedures frequently paired with N10 include: 81001, 87086.

What ICD-9 codes does N10 map to? +

Per CMS GEMs, N10 maps to ICD-9 codes: 59010, 59011. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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