ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E40

Billable / Specific HCC v28: 21 MCC

Kwashiorkor

E40
Block
1
Synonyms
4
LCDs
7
Payer Policies
2
Linked CPTs

About ICD-10-CM E40

ICD-10-CM code E40 represents Kwashiorkor. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E40). The 2026 edition of ICD-10-CM E40 became effective on October 1, 2025.

Coding Tips for E40

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

E40 is a CMS-HCC v28 risk-adjustment code (category 21). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: MCC

E40 is designated MCC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-MCC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag MCC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under E40. Per CMS ICD-10-CM Tabular 2026.

  • Severe malnutrition with nutritional edema with dyspigmentation of skin and hair

Type 1 Excludes

Pure excludes, these codes can never be coded together with E40. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • marasmic kwashiorkor (E42)

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 21
ESRD-HCC
Category 21
RxHCC (Part D)
Category 21

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, MCC

codes Kwashiorkor. As a Major Complication/Comorbidity (MCC), this can shift the DRG assignment to a higher-weighted category, substantial reimbursement impact.

Medicare LCD Coverage for E40

Local Coverage Determinations (LCDs) from CMS MACs that list E40 as a covered diagnosis.

4 LCDs

Showing top 4. Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Magnesium
Article ID: 59186, Effective: 2025-10-01 00:00:00, 4358 covered, 0 non-covered
CPT 83735 →
CMS LCD: Billing and Coding: Vitamin B<sub>12</sub> Injections
Article ID: 57755, Effective: 2024-04-01 00:00:00, 44 covered, 1 non-covered
CPT J3425 →
CMS LCD: Billing and Coding: Vitamin B<sub>12</sub> Injections
Article ID: 57755, Effective: 2024-04-01 00:00:00, 44 covered, 1 non-covered
CPT J3420 →
CMS LCD: Billing and Coding: Serum Magnesium
Article ID: 57189, Effective: 2025-10-16 00:00:00, 1405 covered, 0 non-covered
CPT 83735 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E40.

7 policies

2 Aetna

Hematopoietic Colony-Stimulating Factors (CSFs) - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0055
Nutritional Support - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0061

2 Cigna

Serum Folate and Red Blood Cell Folate Testing - (0567)
Policy ID: MM_0567
Transthoracic Echocardiography in Children - (0523)
Policy ID: MM_0523

3 Medicare

Billing and Coding: Serum Magnesium
Policy ID: ART-57189
Billing and Coding: Vitamin B<sub>12</sub> Injections
Policy ID: ART-57755
Billing and Coding: Magnesium
Policy ID: ART-59186

CPT Codes Commonly Billed with E40

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • J3420 CMS LCD: Billing and Coding: Vitamin B<sub>12</sub> Injections CMS LCD
  • J3425 CMS LCD: Billing and Coding: Vitamin B<sub>12</sub> Injections CMS LCD

Convert E40 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E40 260 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E40, Billing FAQ

Is ICD-10 code E40 billable? +

Yes, E40 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to E40? +

ICD-10 E40 includes: Severe malnutrition with nutritional edema with dyspigmentation of skin and hair.

What codes are Type 1 Excludes for E40? +

Type 1 Excludes (never code together with E40): marasmic kwashiorkor (E42)

Does E40 affect Medicare Advantage HCC risk adjustment? +

Yes. E40 maps to CMS-HCC v28 category 21. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is E40 a CC or MCC for inpatient DRG? +

Yes, this code is designated as MCC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with E40? +

Procedures frequently paired with E40 include: J3420, J3425.

What ICD-9 codes does E40 map to? +

Per CMS GEMs, E40 maps to ICD-9 codes: 260. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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