ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E11.331

Non-Billable Header

Type 2 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema

E11
Block
0
Synonyms
0
LCDs
0
Payer Policies
2
Linked CPTs

About ICD-10-CM E11.331

ICD-10-CM code E11.331 represents Type 2 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema. This is a non-billable header code in the Endocrine, Nutritional, and Metabolic chapter (block E11). The 2026 edition of ICD-10-CM E11.331 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.

Medicare LCD Coverage for E11.331

Local Coverage Determinations (LCDs) from CMS MACs that list E11.331 as a covered diagnosis.

No Medicare LCDs reference E11.331 as covered

This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E11.331.

No commercial payer policies reference E11.331 on file

Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but E11.331 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.

CPT Codes Commonly Billed with E11.331

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • 67028 Intravitreal injection — wet AMD, macular degeneration, diabetic macular edema, diabetic retinopathy, retinal vein occlusion Ophthalmology
  • 67028 Intravitreal injection — wet/dry AMD all stages both eyes, diabetic macular edema, diabetic retinopathy, retinal vein occlusion, macular edema Ophthalmology

Codes Adjacent To E11.331

Other codes in section E08-E13 (Diabetes mellitus).

E08 Diabetes mellitus due to underlying condition (non-billable) E08.0 Diabetes mellitus due to underlying condition with hyperosmolarity (non-billable) E08.00 Diabetes mellitus due to underlying condition with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC) E08.01 Diabetes mellitus due to underlying condition with hyperosmolarity with coma E08.1 Diabetes mellitus due to underlying condition with ketoacidosis (non-billable) E08.10 Diabetes mellitus due to underlying condition with ketoacidosis without coma E08.11 Diabetes mellitus due to underlying condition with ketoacidosis with coma E08.2 Diabetes mellitus due to underlying condition with kidney complications (non-billable) E08.21 Diabetes mellitus due to underlying condition with diabetic nephropathy E08.22 Diabetes mellitus due to underlying condition with diabetic chronic kidney disease E08.29 Diabetes mellitus due to underlying condition with other diabetic kidney complication E08.3 Diabetes mellitus due to underlying condition with ophthalmic complications (non-billable) E08.31 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy (non-billable) E08.311 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy with macular edema E08.319 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy without macular edema E08.32 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy (non-billable) E08.321 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema (non-billable) E08.329 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema (non-billable) E08.33 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy (non-billable) E08.331 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema (non-billable)

ICD-10 E11.331, Billing FAQ

Is ICD-10 code E11.331 billable? +

No, E11.331 is a non-billable header code. Use a more specific child code from block E11 when submitting claims.

What CPT codes are commonly billed with E11.331? +

Procedures frequently paired with E11.331 include: 67028, 67028.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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