ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E10.649

Billable / Specific HCC v28: 18

Type 1 diabetes mellitus with hypoglycemia without coma

E10
Block
0
Synonyms
147
LCDs
22
Payer Policies
0
Linked CPTs

About ICD-10-CM E10.649

ICD-10-CM code E10.649 represents Type 1 diabetes mellitus with hypoglycemia without coma. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E10). The 2026 edition of ICD-10-CM E10.649 became effective on October 1, 2025.

Coding Tips for E10.649

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

E10.649 is a CMS-HCC v28 risk-adjustment code (category 18). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 18
ESRD-HCC
Category 18
RxHCC (Part D)
Category 18

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for E10.649

Local Coverage Determinations (LCDs) from CMS MACs that list E10.649 as a covered diagnosis.

147 LCDs

Showing top 10 of 147 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Magnesium
Article ID: 59186, Effective: 2025-10-01 00:00:00, 4358 covered, 0 non-covered
CPT 83735 →
CMS LCD: Billing and Coding: Implantable Continuous Glucose Monitors (I-CGM)
Article ID: 58213, Effective: 2025-04-01 00:00:00, 373 covered, 1 non-covered
CPT 0446T →
CMS LCD: Billing and Coding: Implantable Continuous Glucose Monitors (I-CGM)
Article ID: 58213, Effective: 2025-04-01 00:00:00, 373 covered, 1 non-covered
CPT 0448T →
CMS LCD: Billing and Coding: Implantable Continuous Glucose Monitors (I-CGM)
Article ID: 58213, Effective: 2025-04-01 00:00:00, 373 covered, 1 non-covered
CPT 0447T →
CMS LCD: Billing and Coding: Homocysteine Level, Serum
Article ID: 56675, Effective: 2024-10-01 00:00:00, 550 covered, 0 non-covered
CPT 83090 →
CMS LCD: Billing and Coding: Implantable Continuous Glucose Monitors (I-CGM)
Article ID: 58116, Effective: 2025-04-01 00:00:00, 373 covered, 1 non-covered
CPT 0446T →
CMS LCD: Billing and Coding: Implantable Continuous Glucose Monitors (I-CGM)
Article ID: 58116, Effective: 2025-04-01 00:00:00, 373 covered, 1 non-covered
CPT 0448T →
CMS LCD: Billing and Coding: Implantable Continuous Glucose Monitors (I-CGM)
Article ID: 58116, Effective: 2025-04-01 00:00:00, 373 covered, 1 non-covered
CPT 0447T →
CMS LCD: Billing and Coding: Routine Foot Care
Article ID: 56680, Effective: 2025-11-01 00:00:00, 1041 covered, 0 non-covered
CPT 11719 →
CMS LCD: Billing and Coding: Routine Foot Care
Article ID: 56680, Effective: 2025-11-01 00:00:00, 1041 covered, 0 non-covered
CPT 11721 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E10.649.

22 policies

5 Medicare

Glucose Monitor - Policy Article
Policy ID: ART-52464
Therapeutic Shoes for Persons with Diabetes - Policy Article
Policy ID: ART-52501
External Infusion Pumps - Policy Article
Policy ID: ART-52507
Billing and Coding: Routine Foot Care
Policy ID: ART-52996
Billing and Coding: Bariatric Surgery for Treatment of Co-Morbidities Conditions Related to Morbid Obesity
Policy ID: ART-54923

CPT Codes Commonly Billed with E10.649

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for E10.649

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert E10.649 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E10.649 25081 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

Codes Adjacent To E10.649

Other codes in section E08-E13 (Diabetes mellitus).

E08 Diabetes mellitus due to underlying condition (non-billable) E08.0 Diabetes mellitus due to underlying condition with hyperosmolarity (non-billable) E08.00 Diabetes mellitus due to underlying condition with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC) E08.01 Diabetes mellitus due to underlying condition with hyperosmolarity with coma E08.1 Diabetes mellitus due to underlying condition with ketoacidosis (non-billable) E08.10 Diabetes mellitus due to underlying condition with ketoacidosis without coma E08.11 Diabetes mellitus due to underlying condition with ketoacidosis with coma E08.2 Diabetes mellitus due to underlying condition with kidney complications (non-billable) E08.21 Diabetes mellitus due to underlying condition with diabetic nephropathy E08.22 Diabetes mellitus due to underlying condition with diabetic chronic kidney disease E08.29 Diabetes mellitus due to underlying condition with other diabetic kidney complication E08.3 Diabetes mellitus due to underlying condition with ophthalmic complications (non-billable) E08.31 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy (non-billable) E08.311 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy with macular edema E08.319 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy without macular edema E08.32 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy (non-billable) E08.321 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema (non-billable) E08.329 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema (non-billable) E08.33 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy (non-billable) E08.331 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema (non-billable)

ICD-10 E10.649, Billing FAQ

Is ICD-10 code E10.649 billable? +

Yes, E10.649 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does E10.649 affect Medicare Advantage HCC risk adjustment? +

Yes. E10.649 maps to CMS-HCC v28 category 18. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What ICD-9 codes does E10.649 map to? +

Per CMS GEMs, E10.649 maps to ICD-9 codes: 25081. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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