Estrogen, and other hormones and factors receptor status
16 codes in this section
About Section Z17
Section Z17 (Z17-Z17) covers estrogen, and other hormones and factors receptor status. It sits within the Factors influencing health status and contact with health services chapter (Z00-Z99). This section contains 16 ICD-10-CM codes, 10 billable diagnoses you can submit on a claim, and 6 non-billable header codes used to organize the hierarchy.
Codes are organized below by 3-character root. Click the root to see all subcodes underneath it, or click any individual code for full coverage data, payer policies, and linked CPT procedures.
Codes in Z17
Grouped by 3-character root code. Click any code for full detail.
| Z17.0 | Estrogen receptor positive status [ER+] | Billable |
| Z17.1 | Estrogen receptor negative status [ER-] | Billable |
| Z17.2 | Progesterone receptor status | Header |
| Z17.21 | Progesterone receptor positive status | Billable |
| Z17.22 | Progesterone receptor negative status | Billable |
| Z17.3 | Human epidermal growth factor 2 receptor | Header |
| Z17.31 | Human epidermal growth factor receptor 2 positive status | Billable |
| Z17.32 | Human epidermal growth factor receptor 2 negative status | Billable |
| Z17.4 | Combined receptor status | Header |
| Z17.41 | Hormone receptor positive | Header |
| Z17.410 | Hormone receptor positive with human epidermal growth factor receptor 2 positive status | Billable |
| Z17.411 | Hormone receptor positive with human epidermal growth factor receptor 2 negative status | Billable |
| Z17.42 | Hormone receptor negative | Header |
| Z17.420 | Hormone receptor negative with human epidermal growth factor receptor 2 positive status | Billable |
| Z17.421 | Hormone receptor negative with human epidermal growth factor receptor 2 negative status | Billable |
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on July 16, 2026.
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