ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 Z15.068

Billable / Specific

Genetic susceptibility to other malignant neoplasm of digestive system

Z15
Block
4
Synonyms
0
LCDs
0
Payer Policies
0
Linked CPTs

About ICD-10-CM Z15.068

ICD-10-CM code Z15.068 represents Genetic susceptibility to other malignant neoplasm of digestive system. This is a billable/specific code in the Factors Influencing Health Status chapter (block Z15). The 2026 edition of ICD-10-CM Z15.068 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under Z15.068. Per CMS ICD-10-CM Tabular 2026.

  • Genetic susceptibility to biliary tract cancer
  • Genetic susceptibility to gastric cancer
  • Genetic susceptibility to pancreatic cancer
  • Genetic susceptibility to small bowel cancer

Medicare LCD Coverage for Z15.068

Local Coverage Determinations (LCDs) from CMS MACs that list Z15.068 as a covered diagnosis.

No Medicare LCDs reference Z15.068 as covered

This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.

Commercial Payer Coverage

Coverage policies from major commercial payers referencing Z15.068.

No commercial payer policies reference Z15.068 on file

Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but Z15.068 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.

CPT Codes Commonly Billed with Z15.068

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for Z15.068

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

ICD-10 Z15.068, Billing FAQ

Is ICD-10 code Z15.068 billable? +

Yes, Z15.068 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to Z15.068? +

ICD-10 Z15.068 includes: Genetic susceptibility to biliary tract cancer; Genetic susceptibility to gastric cancer; Genetic susceptibility to pancreatic cancer, and 1 more clinical synonyms.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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