ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 R21

Billable / Specific

Rash and other nonspecific skin eruption

R21
Block
0
Synonyms
507
LCDs
16
Payer Policies
3
Linked CPTs

About ICD-10-CM R21

ICD-10-CM code R21 represents Rash and other nonspecific skin eruption. This is a billable/specific code in the Symptoms, Signs, and Abnormal Findings chapter (block R21). The 2026 edition of ICD-10-CM R21 became effective on October 1, 2025.

Type 1 Excludes

Pure excludes, these codes can never be coded together with R21. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • specified type of rash- code to condition
  • vesicular eruption (R23.8)

Includes

  • rash NOS

Medicare LCD Coverage for R21

Local Coverage Determinations (LCDs) from CMS MACs that list R21 as a covered diagnosis.

507 LCDs

Showing top 10 of 507 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 95056 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 95004 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 95027 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 82785 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 95076 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 95024 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 95070 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 95028 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 95017 →
CMS LCD: Billing and Coding: Allergy Diagnostic Testing
Article ID: 60390, Effective: , 814 covered, 0 non-covered
CPT 86003 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing R21.

16 policies

1 Cigna

Nucleic Acid Pathogen Testing - (0530)
Policy ID: MM_0530

5 Medicare

Billing and Coding: Zika Virus Testing by PCR and ELISA Methods
Policy ID: ART-55326
Billing and Coding: Cosmetic and Reconstructive Surgery
Policy ID: ART-56587
Billing and Coding: Cosmetic and Reconstructive Surgery
Policy ID: ART-56658
Billing and Coding: Reduction Mammaplasty
Policy ID: ART-56837
Billing and Coding: Allergy Testing
Policy ID: ART-57181

CPT Codes Commonly Billed with R21

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

3 linkages
  • 99202 New patient office visit — fever, headache, abdominal pain, cough, dyspnea, fatigue, dizziness, limb pain, nausea, routine exam, URI, UTI, pharyngitis, otitis, chest pain, weight loss Primary Care
  • 99212 Established patient — URI, UTI, pharyngitis, otitis, dermatitis, rash, viral infection, cellulitis, conjunctivitis, sinusitis, bronchitis, ankle sprain Primary Care
  • 11102 Tangential skin biopsy — uncertain neoplasm skin, actinic keratosis, melanocytic nevi, skin cancer, melanoma, psoriasis, discoid lupus, skin disorder, rash, seborrheic keratosis, benign neoplasm, dermatitis, prurigo, dermatitis herpetiformis Dermatology

Convert R21 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
R21 7821 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 R21, Billing FAQ

Is ICD-10 code R21 billable? +

Yes, R21 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What codes are Type 1 Excludes for R21? +

Type 1 Excludes (never code together with R21): specified type of rash- code to condition; vesicular eruption (R23.8)

What CPT codes are commonly billed with R21? +

Procedures frequently paired with R21 include: 99202, 99212, 11102.

What ICD-9 codes does R21 map to? +

Per CMS GEMs, R21 maps to ICD-9 codes: 7821. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on June 2, 2026.

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