ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 K22.10

Billable / Specific CC

Ulcer of esophagus without bleeding

K22
Block
1
Synonyms
293
LCDs
8
Payer Policies
2
Linked CPTs

About ICD-10-CM K22.10

ICD-10-CM code K22.10 represents Ulcer of esophagus without bleeding. This is a billable/specific code in the Digestive System chapter (block K22). The 2026 edition of ICD-10-CM K22.10 became effective on October 1, 2025.

Coding Tips for K22.10

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Inpatient DRG impact: CC

K22.10 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under K22.10. Per CMS ICD-10-CM Tabular 2026.

  • Ulcer of esophagus NOS

Inpatient DRG Impact, CC

codes Ulcer of esophagus without bleeding. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for K22.10

Local Coverage Determinations (LCDs) from CMS MACs that list K22.10 as a covered diagnosis.

293 LCDs

Showing top 10 of 293 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81227 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81328 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81335 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 0071U →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81383 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81418 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 0073U →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81283 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81408 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81355 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing K22.10.

8 policies

5 Medicare

Billing and Coding: Upper Gastrointestinal Endoscopy and Visualization
Policy ID: ART-56389
Billing and Coding: Computerized Axial Tomography (CT), Thorax
Policy ID: ART-56580
Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy
Policy ID: ART-57063
Billing and Coding: Electrocardiograms
Policy ID: ART-57326
Billing and Coding: Upper Gastrointestinal Endoscopy (Diagnostic and Therapeutic)
Policy ID: ART-57414

CPT Codes Commonly Billed with K22.10

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • 43235 Diagnostic EGD — abdominal pain, nausea, vomiting, GERD, gastric ulcer, gastritis, hematemesis, melena, Barrett esophagus, dysphagia, esophagitis, weight loss, iron deficiency anemia, polyp Gastroenterology
  • 43249 EGD with dilation — Barrett esophagus, esophageal stricture, esophageal web, gastric outlet obstruction, esophageal polyp, gastric polyp Gastroenterology

Convert K22.10 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
K22.10 53020 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 K22.10, Billing FAQ

Is ICD-10 code K22.10 billable? +

Yes, K22.10 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to K22.10? +

ICD-10 K22.10 includes: Ulcer of esophagus NOS.

Is K22.10 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with K22.10? +

Procedures frequently paired with K22.10 include: 43235, 43249.

What ICD-9 codes does K22.10 map to? +

Per CMS GEMs, K22.10 maps to ICD-9 codes: 53020. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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