ICD-10 K21.00
Billable / SpecificGastro-esophageal reflux disease with esophagitis, without bleeding
About ICD-10-CM K21.00
ICD-10-CM code K21.00 represents Gastro-esophageal reflux disease with esophagitis, without bleeding. This is a billable/specific code in the Digestive System chapter (block K21). The 2026 edition of ICD-10-CM K21.00 became effective on October 1, 2025.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under K21.00. Per CMS ICD-10-CM Tabular 2026.
- Reflux esophagitis
Medicare LCD Coverage for K21.00
Local Coverage Determinations (LCDs) from CMS MACs that list K21.00 as a covered diagnosis.
Showing top 10 of 333 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing K21.00.
5 Medicare
4 Aetna
CPT Codes Commonly Billed with K21.00
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- 43284 CMS LCD: Billing and Coding: Lower Esophageal Magnetic Sphincter Augmentation CMS LCD
- 43285 CMS LCD: Billing and Coding: Lower Esophageal Magnetic Sphincter Augmentation CMS LCD
- 43257 CMS LCD: Billing and Coding: Stretta Procedure CMS LCD
- 43999 CMS LCD: Billing and Coding: Select Minimally Invasive GERD Procedures CMS LCD
- 49999 CMS LCD: Billing and Coding: Select Minimally Invasive GERD Procedures CMS LCD
Codes Adjacent To K21.00
Other codes in section K20-K31 (Diseases of esophagus, stomach and duodenum).
ICD-10 K21.00, Billing FAQ
Is ICD-10 code K21.00 billable? +
Yes, K21.00 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to K21.00? +
ICD-10 K21.00 includes: Reflux esophagitis.
What CPT codes are commonly billed with K21.00? +
Procedures frequently paired with K21.00 include: 43284, 43285, 43257, 43999, 49999.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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