ICD-10 I88
Non-Billable HeaderNonspecific lymphadenitis
About ICD-10-CM I88
ICD-10-CM code I88 represents Nonspecific lymphadenitis. This is a non-billable header code in the Circulatory System chapter (block I88). The 2026 edition of ICD-10-CM I88 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Type 1 Excludes
Pure excludes, these codes can never be coded together with I88. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- acute lymphadenitis, except mesenteric (L04.-)
- enlarged lymph nodes NOS (R59.-)
- human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20)
Medicare LCD Coverage for I88
Local Coverage Determinations (LCDs) from CMS MACs that list I88 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing I88.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but I88 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with I88
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To I88
Other codes in section I80-I89 (Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified).
ICD-10 I88, Billing FAQ
Is ICD-10 code I88 billable? +
No, I88 is a non-billable header code. Use a more specific child code from block I88 when submitting claims.
What codes are Type 1 Excludes for I88? +
Type 1 Excludes (never code together with I88): acute lymphadenitis, except mesenteric (L04.-); enlarged lymph nodes NOS (R59.-); human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20)
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 2, 2026.
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