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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 I25.10

Billable / Specific

Atherosclerotic heart disease of native coronary artery without angina pectoris

I25
Block
1
Synonyms
858
LCDs
57
Payer Policies
133
Linked CPTs

About ICD-10-CM I25.10

ICD-10-CM code I25.10 represents Atherosclerotic heart disease of native coronary artery without angina pectoris. This is a billable/specific code in the Circulatory System chapter (block I25). The 2026 edition of ICD-10-CM I25.10 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under I25.10. Per CMS ICD-10-CM Tabular 2026.

  • Atherosclerotic heart disease NOS

Medicare LCD Coverage for I25.10

Local Coverage Determinations (LCDs) from CMS MACs that list I25.10 as a covered diagnosis.

858 LCDs

Showing top 10 of 858 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Non-Invasive Arterial Duplex Ultrasound of the Upper and Lower Extremities
Article ID: 60318, Effective: , 409 covered, 1 non-covered
CPT 93926 →
CMS LCD: Billing and Coding: Non-Invasive Arterial Duplex Ultrasound of the Upper and Lower Extremities
Article ID: 60318, Effective: , 409 covered, 1 non-covered
CPT 93930 →
CMS LCD: Billing and Coding: Non-Invasive Arterial Duplex Ultrasound of the Upper and Lower Extremities
Article ID: 60318, Effective: , 409 covered, 1 non-covered
CPT 93925 →
CMS LCD: Billing and Coding: Non-Invasive Arterial Duplex Ultrasound of the Upper and Lower Extremities
Article ID: 60318, Effective: , 409 covered, 1 non-covered
CPT 93931 →
CMS LCD: Billing and Coding: Ambulatory Electrocardiograph (AECG) Monitoring
Article ID: 59270, Effective: 2025-01-01 00:00:00, 153 covered, 0 non-covered
CPT 93270 →
CMS LCD: Billing and Coding: Ambulatory Electrocardiograph (AECG) Monitoring
Article ID: 59270, Effective: 2025-01-01 00:00:00, 153 covered, 0 non-covered
CPT 93298 →
CMS LCD: Billing and Coding: Ambulatory Electrocardiograph (AECG) Monitoring
Article ID: 59270, Effective: 2025-01-01 00:00:00, 153 covered, 0 non-covered
CPT 93225 →
CMS LCD: Billing and Coding: Ambulatory Electrocardiograph (AECG) Monitoring
Article ID: 59270, Effective: 2025-01-01 00:00:00, 153 covered, 0 non-covered
CPT 93271 →
CMS LCD: Billing and Coding: Ambulatory Electrocardiograph (AECG) Monitoring
Article ID: 59270, Effective: 2025-01-01 00:00:00, 153 covered, 0 non-covered
CPT 93246 →
CMS LCD: Billing and Coding: Ambulatory Electrocardiograph (AECG) Monitoring
Article ID: 59270, Effective: 2025-01-01 00:00:00, 153 covered, 0 non-covered
CPT 93272 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing I25.10.

57 policies

1 Aetna

Positron Emission Tomography (PET) - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0071

3 Cigna

Duplex Scan of Extracranial Arteries - (0542)
Policy ID: MM_0542
Plasma Brain Natriuretic Peptide in the Outpatient Setting - (0028)
Policy ID: MM_0028
Transthoracic Echocardiography in Adults - (0510)
Policy ID: MM_0510

5 Medicare

Billing and Coding: Cardiac Catheterization and Coronary Angiography
Policy ID: ART-52850
Billing and Coding: Non-Invasive Cerebrovascular Arterial Studies
Policy ID: ART-52992
Billing and Coding: Assays for Vitamins and Metabolic Function
Policy ID: ART-56416
Billing and Coding: Cardiology Non-emergent Outpatient Stress Testing
Policy ID: ART-56423
Billing and Coding: Cardiac Computed Tomography (CCT) and Coronary Computed Tomography Angiography (CCTA)
Policy ID: ART-56451

CPT Codes Commonly Billed with I25.10

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

133 linkages
  • 99215 Complex chronic disease management Internal Medicine
  • 99490 Chronic Care Management — 2+ chronic conditions required Internal Medicine
  • 93015 Stress test — chest pain, palpitations, syncope, known CAD Cardiovascular Disease
  • 93458 Left heart catheterization — CAD, ACS, chest pain Cardiovascular Disease
  • 92928 PCI/Stent — coronary artery disease, acute MI Cardiovascular Disease
  • 99204 New patient office visit — multiple chronic conditions: HTN, T2DM, hyperlipidemia, asthma, anxiety, depression, obesity, IBS, COPD, thyroid, anemia, CAD, sleep apnea, psoriasis, RA Primary Care
  • 99205 New patient office visit — complex/high-risk: uncontrolled diabetes, heart failure, COPD exacerbation, cancer, MS, RA, CKD, CAD, recurrent depression, epilepsy, lupus, syncope, cognitive decline Primary Care
  • 99214 Established patient — moderate complexity: uncontrolled HTN, diabetes with complications, multiple chronic conditions, COPD, AFib, CKD, sleep apnea, chronic pain, depression Primary Care
  • 99215 Established patient — high complexity: HF exacerbation, COPD exacerbation, cancer management, MS, advanced CKD, uncontrolled diabetes, recurrent syncope, respiratory failure, liver cirrhosis Primary Care
  • 93000 EKG 12-lead — tachycardia, bradycardia, palpitations, HTN, CAD, AFib, arrhythmia, chest pain, syncope, cardiomyopathy, AV block, bundle branch block, SVT, VT, diabetes screening, abnormal EKG Cardiology

Convert I25.10 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
I25.10 41401 10000
I25.10 4292 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 I25.10, Billing FAQ

Is ICD-10 code I25.10 billable? +

Yes, I25.10 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to I25.10? +

ICD-10 I25.10 includes: Atherosclerotic heart disease NOS.

What CPT codes are commonly billed with I25.10? +

Procedures frequently paired with I25.10 include: 99215, 99490, 93015, 93458, 92928.

What ICD-9 codes does I25.10 map to? +

Per CMS GEMs, I25.10 maps to ICD-9 codes: 41401, 4292. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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