ICD-10 I22
Non-Billable HeaderSubsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction
About ICD-10-CM I22
ICD-10-CM code I22 represents Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction. This is a non-billable header code in the Circulatory System chapter (block I22). The 2026 edition of ICD-10-CM I22 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Type 1 Excludes
Pure excludes, these codes can never be coded together with I22. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- subsequent myocardial infarction, type 2 (I21.A1)
- subsequent myocardial infarction of other type (type 3) (type 4) (type 5) (I21.A9)
Includes
- acute myocardial infarction occurring within four weeks (28 days) of a previous acute myocardial infarction, regardless of site
- cardiac infarction
- coronary (artery) embolism
- coronary (artery) occlusion
- coronary (artery) rupture
- coronary (artery) thrombosis
- infarction of heart, myocardium, or ventricle
- recurrent myocardial infarction
- reinfarction of myocardium
- rupture of heart, myocardium, or ventricle
- subsequent type 1 myocardial infarction
Use Additional Code
When coding I22, also report these additional codes when applicable.
- code, if applicable, to identify:
- exposure to environmental tobacco smoke (Z77.22)
- history of tobacco dependence (Z87.891)
- occupational exposure to environmental tobacco smoke (Z57.31)
- status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)
- tobacco dependence (F17.-)
- tobacco use (Z72.0)
Medicare LCD Coverage for I22
Local Coverage Determinations (LCDs) from CMS MACs that list I22 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing I22.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but I22 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with I22
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- 93000 Electrocardiogram for chest pain evaluation Internal Medicine
- 93015 Stress test for chest pain evaluation Cardiovascular Disease
- 93563 Echocardiogram for chest pain evaluation Cardiovascular Disease
- 93565 Transesophageal echocardiogram for chest pain evaluation Cardiovascular Disease
- 93501 Echocardiogram for chest pain evaluation Cardiovascular Disease
- 93598 Intravascular ultrasound for chest pain evaluation Cardiovascular Disease
- 93618 Implantable cardioverter-defibrillator for ventricular tachycardia Cardiovascular Disease
- 93750 Pacemaker insertion for bradycardia Cardiovascular Disease
- 93799 Unlisted cardiovascular procedure Cardiovascular Disease
- 93567 Transesophageal echocardiogram for chest pain evaluation Cardiovascular Disease
Codes Adjacent To I22
Other codes in section I20-I25 (Ischemic heart diseases).
ICD-10 I22, Billing FAQ
Is ICD-10 code I22 billable? +
No, I22 is a non-billable header code. Use a more specific child code from block I22 when submitting claims.
What codes are Type 1 Excludes for I22? +
Type 1 Excludes (never code together with I22): subsequent myocardial infarction, type 2 (I21.A1); subsequent myocardial infarction of other type (type 3) (type 4) (type 5) (I21.A9)
What CPT codes are commonly billed with I22? +
Procedures frequently paired with I22 include: 93000, 93015, 93563, 93565, 93501.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
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