ICD-10 H21.81
Billable / SpecificFloppy iris syndrome
About ICD-10-CM H21.81
ICD-10-CM code H21.81 represents Floppy iris syndrome. This is a billable/specific code in the Eye and Adnexa chapter (block H21). The 2026 edition of ICD-10-CM H21.81 became effective on October 1, 2025.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under H21.81. Per CMS ICD-10-CM Tabular 2026.
- Intraoperative floppy iris syndrome (IFIS)
Use Additional Code
When coding H21.81, also report these additional codes when applicable.
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Medicare LCD Coverage for H21.81
Local Coverage Determinations (LCDs) from CMS MACs that list H21.81 as a covered diagnosis.
Showing top 10 of 87 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing H21.81.
5 Medicare
CPT Codes Commonly Billed with H21.81
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- 66987 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
- 66840 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
- 66852 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
- 66850 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
- 66940 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
- 66983 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
- 66988 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
- 66982 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
- 66920 CMS LCD: Billing and Coding: Cataract Extraction (including Complex Cataract Surgery) CMS LCD
Convert H21.81 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| H21.81 | 36481 | 00000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To H21.81
Other codes in section H15-H22 (Disorders of sclera, cornea, iris and ciliary body).
ICD-10 H21.81, Billing FAQ
Is ICD-10 code H21.81 billable? +
Yes, H21.81 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to H21.81? +
ICD-10 H21.81 includes: Intraoperative floppy iris syndrome (IFIS).
What CPT codes are commonly billed with H21.81? +
Procedures frequently paired with H21.81 include: 66987, 66840, 66852, 66850, 66940.
What ICD-9 codes does H21.81 map to? +
Per CMS GEMs, H21.81 maps to ICD-9 codes: 36481. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
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