ICD-10 F33
Non-Billable HeaderMajor depressive disorder, recurrent
About ICD-10-CM F33
ICD-10-CM code F33 represents Major depressive disorder, recurrent. This is a non-billable header code in the Mental, Behavioral, and Neurodevelopmental chapter (block F33). The 2026 edition of ICD-10-CM F33 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Type 1 Excludes
Pure excludes, these codes can never be coded together with F33. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- bipolar disorder (F31.-)
- manic episode (F30.-)
Includes
- recurrent episodes of depressive reaction
- recurrent episodes of endogenous depression
- recurrent episodes of major depression
- recurrent episodes of psychogenic depression
- recurrent episodes of reactive depression
- recurrent episodes of seasonal affective disorder
- recurrent episodes of seasonal depressive disorder
- recurrent episodes of vital depression
Medicare LCD Coverage for F33
Local Coverage Determinations (LCDs) from CMS MACs that list F33 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing F33.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but F33 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with F33
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To F33
Other codes in section F30-F39 (Mood [affective] disorders).
ICD-10 F33, Billing FAQ
Is ICD-10 code F33 billable? +
No, F33 is a non-billable header code. Use a more specific child code from block F33 when submitting claims.
What codes are Type 1 Excludes for F33? +
Type 1 Excludes (never code together with F33): bipolar disorder (F31.-); manic episode (F30.-)
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
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