ICD-10 E72
Non-Billable HeaderOther disorders of amino-acid metabolism
About ICD-10-CM E72
ICD-10-CM code E72 represents Other disorders of amino-acid metabolism. This is a non-billable header code in the Endocrine, Nutritional, and Metabolic chapter (block E72). The 2026 edition of ICD-10-CM E72 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Type 1 Excludes
Pure excludes, these codes can never be coded together with E72. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- disorders of:
- aromatic amino-acid metabolism (E70.-)
- branched-chain amino-acid metabolism (E71.0-E71.2)
- fatty-acid metabolism (E71.3)
- purine and pyrimidine metabolism (E79.-)
- gout (M1A.-, M10.-)
Medicare LCD Coverage for E72
Local Coverage Determinations (LCDs) from CMS MACs that list E72 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing E72.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but E72 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with E72
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To E72
Other codes in section E70-E88 (Metabolic disorders).
ICD-10 E72, Billing FAQ
Is ICD-10 code E72 billable? +
No, E72 is a non-billable header code. Use a more specific child code from block E72 when submitting claims.
What codes are Type 1 Excludes for E72? +
Type 1 Excludes (never code together with E72): disorders of:; aromatic amino-acid metabolism (E70.-); branched-chain amino-acid metabolism (E71.0-E71.2)
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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