ICD-10 E53.8
Billable / SpecificDeficiency of other specified B group vitamins
About ICD-10-CM E53.8
ICD-10-CM code E53.8 represents Deficiency of other specified B group vitamins. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E53). The 2026 edition of ICD-10-CM E53.8 became effective on October 1, 2025.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under E53.8. Per CMS ICD-10-CM Tabular 2026.
- Biotin deficiency
- Cyanocobalamin deficiency
- Folate deficiency
- Folic acid deficiency
- Pantothenic acid deficiency
- Vitamin B12 deficiency
Type 1 Excludes
Pure excludes, these codes can never be coded together with E53.8. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- folate deficiency anemia (D52.-)
- vitamin B12 deficiency anemia (D51.-)
Medicare LCD Coverage for E53.8
Local Coverage Determinations (LCDs) from CMS MACs that list E53.8 as a covered diagnosis.
Showing top 10 of 114 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing E53.8.
5 Medicare
3 Aetna
Convert E53.8 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| E53.8 | 2662 | 10000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To E53.8
Other codes in section E50-E64 (Other nutritional deficiencies).
ICD-10 E53.8, Billing FAQ
Is ICD-10 code E53.8 billable? +
Yes, E53.8 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to E53.8? +
ICD-10 E53.8 includes: Biotin deficiency; Cyanocobalamin deficiency; Folate deficiency, and 3 more clinical synonyms.
What codes are Type 1 Excludes for E53.8? +
Type 1 Excludes (never code together with E53.8): folate deficiency anemia (D52.-); vitamin B12 deficiency anemia (D51.-)
What CPT codes are commonly billed with E53.8? +
Procedures frequently paired with E53.8 include: J3420, J3425.
What ICD-9 codes does E53.8 map to? +
Per CMS GEMs, E53.8 maps to ICD-9 codes: 2662. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on July 16, 2026.
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