ICD-10 E52
Billable / SpecificNiacin deficiency [pellagra]
About ICD-10-CM E52
ICD-10-CM code E52 represents Niacin deficiency [pellagra]. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E52). The 2026 edition of ICD-10-CM E52 became effective on October 1, 2025.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under E52. Per CMS ICD-10-CM Tabular 2026.
- Niacin (-tryptophan) deficiency
- Nicotinamide deficiency
- Pellagra (alcoholic)
Type 1 Excludes
Pure excludes, these codes can never be coded together with E52. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- sequelae of niacin deficiency (E64.8)
Medicare LCD Coverage for E52
Local Coverage Determinations (LCDs) from CMS MACs that list E52 as a covered diagnosis.
Showing top 10 of 55 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing E52.
1 Cigna
5 Medicare
CPT Codes Commonly Billed with E52
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Convert E52 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| E52 | 2652 | 00000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To E52
Other codes in section E50-E64 (Other nutritional deficiencies).
ICD-10 E52, Billing FAQ
Is ICD-10 code E52 billable? +
Yes, E52 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to E52? +
ICD-10 E52 includes: Niacin (-tryptophan) deficiency; Nicotinamide deficiency; Pellagra (alcoholic).
What codes are Type 1 Excludes for E52? +
Type 1 Excludes (never code together with E52): sequelae of niacin deficiency (E64.8)
What ICD-9 codes does E52 map to? +
Per CMS GEMs, E52 maps to ICD-9 codes: 2652. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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