ICD-10 E25
Non-Billable HeaderAdrenogenital disorders
About ICD-10-CM E25
ICD-10-CM code E25 represents Adrenogenital disorders. This is a non-billable header code in the Endocrine, Nutritional, and Metabolic chapter (block E25). The 2026 edition of ICD-10-CM E25 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Type 1 Excludes
Pure excludes, these codes can never be coded together with E25. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- indeterminate sex and pseudohermaphroditism (Q56)
- chromosomal abnormalities (Q90-Q99)
Includes
- adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
- Female adrenal pseudohermaphroditism
- Female heterosexual precocious pseudopuberty
- Male isosexual precocious pseudopuberty
- Male macrogenitosomia praecox
- Male sexual precocity with adrenal hyperplasia
- Male virilization (female)
Medicare LCD Coverage for E25
Local Coverage Determinations (LCDs) from CMS MACs that list E25 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing E25.
1 Aetna
CPT Codes Commonly Billed with E25
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To E25
Other codes in section E20-E35 (Disorders of other endocrine glands).
ICD-10 E25, Billing FAQ
Is ICD-10 code E25 billable? +
No, E25 is a non-billable header code. Use a more specific child code from block E25 when submitting claims.
What codes are Type 1 Excludes for E25? +
Type 1 Excludes (never code together with E25): indeterminate sex and pseudohermaphroditism (Q56); chromosomal abnormalities (Q90-Q99)
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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