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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D75.821

Billable / Specific HCC v28: 48

Non-immune heparin-induced thrombocytopenia

D75
Block
2
Synonyms
30
LCDs
4
Payer Policies
3
Linked CPTs

About ICD-10-CM D75.821

ICD-10-CM code D75.821 represents Non-immune heparin-induced thrombocytopenia. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D75). The 2026 edition of ICD-10-CM D75.821 became effective on October 1, 2025.

Coding Tips for D75.821

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D75.821 is a CMS-HCC v28 risk-adjustment code (category 48). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D75.821. Per CMS ICD-10-CM Tabular 2026.

  • Non-immune HIT
  • Type 1 heparin-induced thrombocytopenia

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 48
ESRD-HCC
Category 48
RxHCC (Part D)
Category 48

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for D75.821

Local Coverage Determinations (LCDs) from CMS MACs that list D75.821 as a covered diagnosis.

30 LCDs

Showing top 10 of 30 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 88189 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 86360 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 86361 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 88187 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 86359 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 86356 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 88188 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 88184 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 88185 →
CMS LCD: Billing and Coding: Flow Cytometry
Article ID: 56464, Effective: 2026-03-05 00:00:00, 1361 covered, 0 non-covered
CPT 86367 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D75.821.

4 policies

4 Medicare

Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: Erythropoiesis Stimulating Agents (ESAs)
Policy ID: ART-56795
Billing and Coding: Non-Invasive Peripheral Venous Vascular and Hemodialysis Access Studies
Policy ID: ART-57594
Billing and Coding: MolDX: Next-Generation Sequencing Lab-Developed Tests for Myeloid Malignancies and Suspected Myeloid Malignancies
Policy ID: ART-57873

CPT Codes Commonly Billed with D75.821

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

3 linkages
  • 93990 CMS LCD: Billing and Coding: Non-Invasive Peripheral Venous Vascular and Hemodialysis Access Studies CMS LCD
  • 93985 CMS LCD: Billing and Coding: Non-Invasive Peripheral Venous Vascular and Hemodialysis Access Studies CMS LCD
  • 93986 CMS LCD: Billing and Coding: Non-Invasive Peripheral Venous Vascular and Hemodialysis Access Studies CMS LCD

ICD-10 D75.821, Billing FAQ

Is ICD-10 code D75.821 billable? +

Yes, D75.821 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D75.821? +

ICD-10 D75.821 includes: Non-immune HIT; Type 1 heparin-induced thrombocytopenia.

Does D75.821 affect Medicare Advantage HCC risk adjustment? +

Yes. D75.821 maps to CMS-HCC v28 category 48. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What CPT codes are commonly billed with D75.821? +

Procedures frequently paired with D75.821 include: 93990, 93985, 93986.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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