ICD-10 D46
Non-Billable HeaderMyelodysplastic syndromes
About ICD-10-CM D46
ICD-10-CM code D46 represents Myelodysplastic syndromes. This is a non-billable header code in the Neoplasms chapter (block D46). The 2026 edition of ICD-10-CM D46 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Type 2 Excludes
Not included here, the excluded code is not part of D46, but a patient may have both conditions at the same time. Both codes may be coded together when applicable.
- drug-induced aplastic anemia (D61.1)
Use Additional Code
When coding D46, also report these additional codes when applicable.
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Medicare LCD Coverage for D46
Local Coverage Determinations (LCDs) from CMS MACs that list D46 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing D46.
1 Cigna
CPT Codes Commonly Billed with D46
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To D46
Other codes in section D37-D48 (Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes).
ICD-10 D46, Billing FAQ
Is ICD-10 code D46 billable? +
No, D46 is a non-billable header code. Use a more specific child code from block D46 when submitting claims.
What codes are Type 2 Excludes for D46? +
Type 2 Excludes (may be coded together when both conditions exist): drug-induced aplastic anemia (D61.1)
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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