ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D31.21

Billable / Specific

Benign neoplasm of right retina

D31
Block
0
Synonyms
151
LCDs
17
Payer Policies
9
Linked CPTs

About ICD-10-CM D31.21

ICD-10-CM code D31.21 represents Benign neoplasm of right retina. This is a billable/specific code in the Neoplasms chapter (block D31). The 2026 edition of ICD-10-CM D31.21 became effective on October 1, 2025.

Medicare LCD Coverage for D31.21

Local Coverage Determinations (LCDs) from CMS MACs that list D31.21 as a covered diagnosis.

151 LCDs

Showing top 10 of 151 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92201 →
CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92250 →
CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92202 →
CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92227 →
CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92228 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64420 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 20561 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64415 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64447 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64448 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D31.21.

17 policies

5 Medicare

Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Policy ID: ART-53060
Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: Visual Fields Testing
Policy ID: ART-56551
Billing and Coding: Computerized Axial Tomography (CT), Thorax
Policy ID: ART-56580
Billing and Coding: Implantable Infusion Pump
Policy ID: ART-56695

CPT Codes Commonly Billed with D31.21

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

9 linkages
  • 92235 CMS LCD: Billing and Coding: Ophthalmic Angiography (Fluorescein and Indocyanine Green) CMS LCD
  • 92240 CMS LCD: Billing and Coding: Ophthalmic Angiography (Fluorescein and Indocyanine Green) CMS LCD
  • 92242 CMS LCD: Billing and Coding: Ophthalmic Angiography (Fluorescein and Indocyanine Green) CMS LCD
  • 92228 CMS LCD: Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography) CMS LCD
  • 92201 CMS LCD: Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography) CMS LCD
  • 92202 CMS LCD: Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography) CMS LCD
  • 92250 CMS LCD: Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography) CMS LCD
  • 92227 CMS LCD: Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography) CMS LCD
  • 92132 CMS LCD: Billing and Coding: Scanning Computerized Ophthalmic Diagnostic Imaging (SCODI) CMS LCD

Convert D31.21 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D31.21 2245 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D31.21, Billing FAQ

Is ICD-10 code D31.21 billable? +

Yes, D31.21 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What CPT codes are commonly billed with D31.21? +

Procedures frequently paired with D31.21 include: 92235, 92240, 92242, 92228, 92201.

What ICD-9 codes does D31.21 map to? +

Per CMS GEMs, D31.21 maps to ICD-9 codes: 2245. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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