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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D21.12

Billable / Specific

Benign neoplasm of connective and other soft tissue of left upper limb, including shoulder

D21
Block
0
Synonyms
141
LCDs
6
Payer Policies
2
Linked CPTs

About ICD-10-CM D21.12

ICD-10-CM code D21.12 represents Benign neoplasm of connective and other soft tissue of left upper limb, including shoulder. This is a billable/specific code in the Neoplasms chapter (block D21). The 2026 edition of ICD-10-CM D21.12 became effective on October 1, 2025.

Medicare LCD Coverage for D21.12

Local Coverage Determinations (LCDs) from CMS MACs that list D21.12 as a covered diagnosis.

141 LCDs

Showing top 10 of 141 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64420 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 20561 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64415 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64447 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64448 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64416 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64405 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64454 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64425 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64450 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D21.12.

6 policies

5 Medicare

Billing and Coding: Removal of Benign and Malignant Skin Lesions
Policy ID: ART-56346
Billing and Coding: Computerized Axial Tomography (CT), Thorax
Policy ID: ART-56580
Billing and Coding: Implantable Infusion Pump
Policy ID: ART-56695
Billing and Coding: Nonvascular Extremity Ultrasound
Policy ID: ART-56787
Billing and Coding: Peripheral Nerve Blocks
Policy ID: ART-57452

CPT Codes Commonly Billed with D21.12

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • 76882 CMS LCD: Billing and Coding: Nonvascular Extremity Ultrasound CMS LCD
  • 76881 CMS LCD: Billing and Coding: Nonvascular Extremity Ultrasound CMS LCD

Convert D21.12 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D21.12 2152 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

Codes Adjacent To D21.12

Other codes in section D10-D36 (Benign neoplasms, except benign neuroendocrine tumors).

D10 Benign neoplasm of mouth and pharynx (non-billable) D10.0 Benign neoplasm of lip D10.1 Benign neoplasm of tongue D10.2 Benign neoplasm of floor of mouth D10.3 Benign neoplasm of other and unspecified parts of mouth (non-billable) D10.30 Benign neoplasm of unspecified part of mouth D10.39 Benign neoplasm of other parts of mouth D10.4 Benign neoplasm of tonsil D10.5 Benign neoplasm of other parts of oropharynx D10.6 Benign neoplasm of nasopharynx D10.7 Benign neoplasm of hypopharynx D10.9 Benign neoplasm of pharynx, unspecified D11 Benign neoplasm of major salivary glands (non-billable) D11.0 Benign neoplasm of parotid gland D11.7 Benign neoplasm of other major salivary glands D11.9 Benign neoplasm of major salivary gland, unspecified D12 Benign neoplasm of colon, rectum, anus and anal canal (non-billable) D12.0 Benign neoplasm of cecum D12.1 Benign neoplasm of appendix D12.2 Benign neoplasm of ascending colon

ICD-10 D21.12, Billing FAQ

Is ICD-10 code D21.12 billable? +

Yes, D21.12 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What CPT codes are commonly billed with D21.12? +

Procedures frequently paired with D21.12 include: 76882, 76881.

What ICD-9 codes does D21.12 map to? +

Per CMS GEMs, D21.12 maps to ICD-9 codes: 2152. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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