ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 C88.9

Non-Billable Header

Malignant immunoproliferative disease, unspecified

C88
Block
1
Synonyms
0
LCDs
2
Payer Policies
0
Linked CPTs

About ICD-10-CM C88.9

ICD-10-CM code C88.9 represents Malignant immunoproliferative disease, unspecified. This is a non-billable header code in the chapter (block C88). The 2026 edition of ICD-10-CM C88.9 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under C88.9. Per CMS ICD-10-CM Tabular 2026.

  • Immunoproliferative disease NOS

Medicare LCD Coverage for C88.9

Local Coverage Determinations (LCDs) from CMS MACs that list C88.9 as a covered diagnosis.

No Medicare LCDs reference C88.9 as covered

This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.

Commercial Payer Coverage

Coverage policies from major commercial payers referencing C88.9.

2 policies

2 Cigna

Head and Neck Ultrasound - (0549)
Policy ID: MM_0549
Transthoracic Echocardiography in Adults - (0510)
Policy ID: MM_0510

CPT Codes Commonly Billed with C88.9

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for C88.9

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert C88.9 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
C88.9 20380 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

Codes Adjacent To C88.9

Other codes in section C81-C96 (Malignant neoplasms of lymphoid, hematopoietic and related tissue).

C81 Hodgkin lymphoma (non-billable) C81.0 Nodular lymphocyte predominant Hodgkin lymphoma (non-billable) C81.00 Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site C81.01 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck C81.02 Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes C81.03 Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes C81.04 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.05 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb C81.06 Nodular lymphocyte predominant Hodgkin lymphoma, intrapelvic lymph nodes C81.07 Nodular lymphocyte predominant Hodgkin lymphoma, spleen C81.08 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites C81.09 Nodular lymphocyte predominant Hodgkin lymphoma, extranodal and solid organ sites C81.0A Nodular lymphocyte predominant Hodgkin lymphoma, in remission C81.1 Nodular sclerosis Hodgkin lymphoma (non-billable) C81.10 Nodular sclerosis Hodgkin lymphoma, unspecified site C81.11 Nodular sclerosis Hodgkin lymphoma, lymph nodes of head, face, and neck C81.12 Nodular sclerosis Hodgkin lymphoma, intrathoracic lymph nodes C81.13 Nodular sclerosis Hodgkin lymphoma, intra-abdominal lymph nodes C81.14 Nodular sclerosis Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.15 Nodular sclerosis Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

ICD-10 C88.9, Billing FAQ

Is ICD-10 code C88.9 billable? +

No, C88.9 is a non-billable header code. Use a more specific child code from block C88 when submitting claims.

What other names or terms map to C88.9? +

ICD-10 C88.9 includes: Immunoproliferative disease NOS.

What ICD-9 codes does C88.9 map to? +

Per CMS GEMs, C88.9 maps to ICD-9 codes: 20380. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on June 1, 2026.

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