ICD-10 C88.00
Billable / Specific HCC v28: 23Waldenstrom macroglobulinemia not having achieved remission
About ICD-10-CM C88.00
ICD-10-CM code C88.00 represents Waldenstrom macroglobulinemia not having achieved remission. This is a billable/specific code in the chapter (block C88). The 2026 edition of ICD-10-CM C88.00 became effective on October 1, 2025.
Coding Tips for C88.00
Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.
C88.00 is a CMS-HCC v28 risk-adjustment code (category 23). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under C88.00. Per CMS ICD-10-CM Tabular 2026.
- Lymphoplasmacytic lymphoma with IgM-production, NOS
- Lymphoplasmacytic lymphoma with IgM-production not having achieved remission
- Lymphoplasmacytic lymphoma with IgM-production with failed remission
- Macroglobulinemia (idiopathic) (primary) NOS
- Macroglobulinemia (idiopathic) (primary) not having achieved remission
- Macroglobulinemia (idiopathic) (primary) with failed remission
- Waldenström macroglobulinemia NOS
- Waldenström macroglobulinemia with failed remission
Medicare Advantage HCC Impact
Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.
Medicare LCD Coverage for C88.00
Local Coverage Determinations (LCDs) from CMS MACs that list C88.00 as a covered diagnosis.
Showing top 10 of 988 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing C88.00.
3 Cigna
5 Medicare
CPT Codes Commonly Billed with C88.00
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
Codes Adjacent To C88.00
Other codes in section C81-C96 (Malignant neoplasms of lymphoid, hematopoietic and related tissue).
ICD-10 C88.00, Billing FAQ
Is ICD-10 code C88.00 billable? +
Yes, C88.00 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to C88.00? +
ICD-10 C88.00 includes: Lymphoplasmacytic lymphoma with IgM-production, NOS; Lymphoplasmacytic lymphoma with IgM-production not having achieved remission; Lymphoplasmacytic lymphoma with IgM-production with failed remission, and 5 more clinical synonyms.
Does C88.00 affect Medicare Advantage HCC risk adjustment? +
Yes. C88.00 maps to CMS-HCC v28 category 23. Capture this diagnosis annually for accurate Medicare Advantage risk score.
What CPT codes are commonly billed with C88.00? +
Procedures frequently paired with C88.00 include: 0077U, J2791, J2792.
Get the full PayerReady toolkit
Free access to CPT/ICD-10 lookup, denial appeals, fee comparator, and claim auditing with credentialing enrollment.
Start free →Run this code through our claim audit tool
Check NCCI bundling, MUE limits, and modifier logic before submission.
Try the auditor →Did this page help?
Quick signal so we know what to improve.
If you want a code reference page that doesn't exist yet, email coding@payerready.com.
Tell us what's missing or wrong: coding@payerready.com. We respond within 5 business days.
Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
Powered by 11K CPT · 98K ICD-10 · 860K MPFS rates · 4.5M NCCI edits · 9.5M NPIs. Our data methodology · About our coding team