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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 C83.398

Billable / Specific HCC v28: 10 CC

Diffuse large B-cell lymphoma of other extranodal and solid organ sites

C83
Block
0
Synonyms
1,213
LCDs
45
Payer Policies
24
Linked CPTs

About ICD-10-CM C83.398

ICD-10-CM code C83.398 represents Diffuse large B-cell lymphoma of other extranodal and solid organ sites. This is a billable/specific code in the chapter (block C83). The 2026 edition of ICD-10-CM C83.398 became effective on October 1, 2025.

Coding Tips for C83.398

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

C83.398 is a CMS-HCC v28 risk-adjustment code (category 10). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: CC

C83.398 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 10
ESRD-HCC
Category 10
RxHCC (Part D)
Category 10

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, CC

codes Diffuse large B-cell lymphoma of other extranodal and solid organ sites. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for C83.398

Local Coverage Determinations (LCDs) from CMS MACs that list C83.398 as a covered diagnosis.

1,213 LCDs

Showing top 10 of 1,213 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77402 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77371 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 61797 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT G0339 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77338 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77432 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 61800 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77372 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77435 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77407 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing C83.398.

45 policies

5 Medicare

Billing and Coding: Bevacizumab and biosimilars
Policy ID: ART-52370
Oral Anticancer Drugs - Policy Article
Policy ID: ART-52479
Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
Policy ID: ART-52480
Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID� Update
Policy ID: ART-53101
Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID�
Policy ID: ART-54188

CPT Codes Commonly Billed with C83.398

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

24 linkages
  • 44408 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 45379 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 44406 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 45390 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 45392 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 44394 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 44402 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 44390 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 44405 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD
  • 44388 CMS LCD: Billing and Coding: Diagnostic Colonoscopy CMS LCD

Codes Adjacent To C83.398

Other codes in section C81-C96 (Malignant neoplasms of lymphoid, hematopoietic and related tissue).

C81 Hodgkin lymphoma (non-billable) C81.0 Nodular lymphocyte predominant Hodgkin lymphoma (non-billable) C81.00 Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site C81.01 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck C81.02 Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes C81.03 Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes C81.04 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.05 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb C81.06 Nodular lymphocyte predominant Hodgkin lymphoma, intrapelvic lymph nodes C81.07 Nodular lymphocyte predominant Hodgkin lymphoma, spleen C81.08 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites C81.09 Nodular lymphocyte predominant Hodgkin lymphoma, extranodal and solid organ sites C81.0A Nodular lymphocyte predominant Hodgkin lymphoma, in remission C81.1 Nodular sclerosis Hodgkin lymphoma (non-billable) C81.10 Nodular sclerosis Hodgkin lymphoma, unspecified site C81.11 Nodular sclerosis Hodgkin lymphoma, lymph nodes of head, face, and neck C81.12 Nodular sclerosis Hodgkin lymphoma, intrathoracic lymph nodes C81.13 Nodular sclerosis Hodgkin lymphoma, intra-abdominal lymph nodes C81.14 Nodular sclerosis Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.15 Nodular sclerosis Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

ICD-10 C83.398, Billing FAQ

Is ICD-10 code C83.398 billable? +

Yes, C83.398 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does C83.398 affect Medicare Advantage HCC risk adjustment? +

Yes. C83.398 maps to CMS-HCC v28 category 10. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is C83.398 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with C83.398? +

Procedures frequently paired with C83.398 include: 44408, 45379, 44406, 45390, 45392.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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