ICD-10 C83.390
Billable / Specific HCC v28: 10 CCPrimary central nervous system lymphoma
About ICD-10-CM C83.390
ICD-10-CM code C83.390 represents Primary central nervous system lymphoma. This is a billable/specific code in the chapter (block C83). The 2026 edition of ICD-10-CM C83.390 became effective on October 1, 2025.
Coding Tips for C83.390
Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.
C83.390 is a CMS-HCC v28 risk-adjustment code (category 10). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.
C83.390 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under C83.390. Per CMS ICD-10-CM Tabular 2026.
- PCNSL of brain
- PCNSL of meninges
- PCNSL of spinal cord
- PCNSL NOS
Type 1 Excludes
Pure excludes, these codes can never be coded together with C83.390. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- Primary central nervous system lymphoma, Burkitt (C83.79)
- Primary central nervous system lymphoma, lymphoblastic (C83.59)
- Primary central nervous system lymphoma, other (C83.89)
- Primary central nervous system lymphoma, peripheral T-cell (C84.49)
Medicare Advantage HCC Impact
Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.
Inpatient DRG Impact, CC
codes Primary central nervous system lymphoma. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.
Medicare LCD Coverage for C83.390
Local Coverage Determinations (LCDs) from CMS MACs that list C83.390 as a covered diagnosis.
Showing top 10 of 1,067 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing C83.390.
5 Medicare
CPT Codes Commonly Billed with C83.390
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To C83.390
Other codes in section C81-C96 (Malignant neoplasms of lymphoid, hematopoietic and related tissue).
ICD-10 C83.390, Billing FAQ
Is ICD-10 code C83.390 billable? +
Yes, C83.390 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to C83.390? +
ICD-10 C83.390 includes: PCNSL of brain; PCNSL of meninges; PCNSL of spinal cord, and 1 more clinical synonyms.
What codes are Type 1 Excludes for C83.390? +
Type 1 Excludes (never code together with C83.390): Primary central nervous system lymphoma, Burkitt (C83.79); Primary central nervous system lymphoma, lymphoblastic (C83.59); Primary central nervous system lymphoma, other (C83.89)
Does C83.390 affect Medicare Advantage HCC risk adjustment? +
Yes. C83.390 maps to CMS-HCC v28 category 10. Capture this diagnosis annually for accurate Medicare Advantage risk score.
Is C83.390 a CC or MCC for inpatient DRG? +
Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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