ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 C39.0

Billable / Specific HCC v28: 11

Malignant neoplasm of upper respiratory tract, part unspecified

C39
Block
0
Synonyms
368
LCDs
33
Payer Policies
0
Linked CPTs

About ICD-10-CM C39.0

ICD-10-CM code C39.0 represents Malignant neoplasm of upper respiratory tract, part unspecified. This is a billable/specific code in the Neoplasms chapter (block C39). The 2026 edition of ICD-10-CM C39.0 became effective on October 1, 2025.

Coding Tips for C39.0

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

C39.0 is a CMS-HCC v28 risk-adjustment code (category 11). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 11
ESRD-HCC
Category 11
RxHCC (Part D)
Category 11

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for C39.0

Local Coverage Determinations (LCDs) from CMS MACs that list C39.0 as a covered diagnosis.

368 LCDs

Showing top 10 of 368 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Predictive Testing in Cancer
Article ID: 60240, Effective: , 680 covered, 0 non-covered
CPT 81479 →
CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Predictive Testing in Cancer
Article ID: 60309, Effective: , 680 covered, 0 non-covered
CPT 81479 →
CMS LCD: Billing and Coding: MolDX: Plasma-Based Genomic Profiling in Solid Tumors
Article ID: 57867, Effective: 2025-07-01 00:00:00, 622 covered, 0 non-covered
CPT 0179U →
CMS LCD: Billing and Coding: MolDX: Plasma-Based Genomic Profiling in Solid Tumors
Article ID: 57867, Effective: 2025-07-01 00:00:00, 622 covered, 0 non-covered
CPT 81479 →
CMS LCD: Billing and Coding: MolDX: Plasma-Based Genomic Profiling in Solid Tumors
Article ID: 57867, Effective: 2025-07-01 00:00:00, 622 covered, 0 non-covered
CPT 81462 →
CMS LCD: Billing and Coding: MolDX: Plasma-Based Genomic Profiling in Solid Tumors
Article ID: 57867, Effective: 2025-07-01 00:00:00, 622 covered, 0 non-covered
CPT 81445 →
CMS LCD: Billing and Coding: MolDX: Plasma-Based Genomic Profiling in Solid Tumors
Article ID: 57867, Effective: 2025-07-01 00:00:00, 622 covered, 0 non-covered
CPT 0571U →
CMS LCD: Billing and Coding: MolDX: Plasma-Based Genomic Profiling in Solid Tumors
Article ID: 57867, Effective: 2025-07-01 00:00:00, 622 covered, 0 non-covered
CPT 0485U →
CMS LCD: Billing and Coding: MolDX: Plasma-Based Genomic Profiling in Solid Tumors
Article ID: 57867, Effective: 2025-07-01 00:00:00, 622 covered, 0 non-covered
CPT 81463 →
CMS LCD: Billing and Coding: MolDX: Plasma-Based Genomic Profiling in Solid Tumors
Article ID: 57867, Effective: 2025-07-01 00:00:00, 622 covered, 0 non-covered
CPT 81464 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing C39.0.

33 policies

2 Cigna

Transthoracic Echocardiography in Adults - (0510)
Policy ID: MM_0510
Transthoracic Echocardiography in Children - (0523)
Policy ID: MM_0523

5 Medicare

Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
Policy ID: ART-52480
Billing and Coding: Proton Beam Therapy
Policy ID: ART-55315
Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-55717
Billing and Coding: Erythropoiesis Stimulating Agents (ESA)
Policy ID: ART-56462
Billing and Coding: Computerized Axial Tomography (CT), Thorax
Policy ID: ART-56580

CPT Codes Commonly Billed with C39.0

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for C39.0

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert C39.0 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
C39.0 1650 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 C39.0, Billing FAQ

Is ICD-10 code C39.0 billable? +

Yes, C39.0 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does C39.0 affect Medicare Advantage HCC risk adjustment? +

Yes. C39.0 maps to CMS-HCC v28 category 11. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What ICD-9 codes does C39.0 map to? +

Per CMS GEMs, C39.0 maps to ICD-9 codes: 1650. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on June 1, 2026.

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