ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 C15.5

Billable / Specific HCC v28: 9 CC

Malignant neoplasm of lower third of esophagus

C15
Block
0
Synonyms
949
LCDs
53
Payer Policies
81
Linked CPTs

About ICD-10-CM C15.5

ICD-10-CM code C15.5 represents Malignant neoplasm of lower third of esophagus. This is a billable/specific code in the Neoplasms chapter (block C15). The 2026 edition of ICD-10-CM C15.5 became effective on October 1, 2025.

Coding Tips for C15.5

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

C15.5 is a CMS-HCC v28 risk-adjustment code (category 9). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: CC

C15.5 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Type 1 Excludes

Pure excludes, these codes can never be coded together with C15.5. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • malignant neoplasm of cardio-esophageal junction (C16.0)

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 9
ESRD-HCC
Category 9
RxHCC (Part D)
Category 9

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, CC

codes Malignant neoplasm of lower third of esophagus. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for C15.5

Local Coverage Determinations (LCDs) from CMS MACs that list C15.5 as a covered diagnosis.

949 LCDs

Showing top 10 of 949 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77402 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77371 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 61797 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT G0339 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77338 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77432 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 61800 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77372 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77435 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77407 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing C15.5.

53 policies

5 Medicare

Billing and Coding: Paclitaxel (e.g., Taxol�/Abraxane �)
Policy ID: ART-52450
Oral Anticancer Drugs - Policy Article
Policy ID: ART-52479
Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
Policy ID: ART-52480
Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID� Update
Policy ID: ART-53101
Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID�
Policy ID: ART-54188

CPT Codes Commonly Billed with C15.5

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

81 linkages
  • 83735 CMS LCD: Billing and Coding: Magnesium CMS LCD
  • 81540 CMS LCD: Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID� Update CMS LCD
  • 43244 CMS LCD: Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy CMS LCD
  • 43251 CMS LCD: Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy CMS LCD
  • 43241 CMS LCD: Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy CMS LCD
  • 43243 CMS LCD: Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy CMS LCD
  • 43270 CMS LCD: Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy CMS LCD
  • 43253 CMS LCD: Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy CMS LCD
  • 43246 CMS LCD: Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy CMS LCD
  • 43233 CMS LCD: Billing and Coding: Diagnostic and Therapeutic Esophagogastroduodenoscopy CMS LCD

Convert C15.5 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
C15.5 1502 10000
C15.5 1505 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 C15.5, Billing FAQ

Is ICD-10 code C15.5 billable? +

Yes, C15.5 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What codes are Type 1 Excludes for C15.5? +

Type 1 Excludes (never code together with C15.5): malignant neoplasm of cardio-esophageal junction (C16.0)

Does C15.5 affect Medicare Advantage HCC risk adjustment? +

Yes. C15.5 maps to CMS-HCC v28 category 9. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is C15.5 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with C15.5? +

Procedures frequently paired with C15.5 include: 83735, 81540, 43244, 43251, 43241.

What ICD-9 codes does C15.5 map to? +

Per CMS GEMs, C15.5 maps to ICD-9 codes: 1502, 1505. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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