CPT 38207
Global XXXCryopreserve stem cells
CPT 38207 Billing & Documentation Guide
CPT code 38207 (Cryopreserve stem cells) is classified under Surgery (Respiratory/Cardiovascular) with a global period indicator of XXX. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 0.87, a non-facility practice expense RVU of 0.19, and a malpractice RVU of 0.08, a total non-facility RVU of 1.14 and facility RVU of 1.14. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $38.56, though rates vary from $35.89 to $51.82 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 38207, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 38207 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Invalid for Medicare; not separately payable
No global period (E/M and other non-procedural services)
MUE Limit (Medically Unlikely Edits)
Submitting more than 0 units of 38207 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 38207
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 0.87 | 0.87 |
| Practice Expense RVU | 0.19 | 0.19 |
| Malpractice RVU | 0.08 | 0.08 |
| Total RVU | 1.14 | 1.14 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 38207
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $39.06 | $39.06 | $37.94 - $42.84 | 29 |
| Florida | $40.63 | $40.63 | $39.14 - $42.42 | 3 |
| Georgia | $38.35 | $38.35 | $37.9 - $38.8 | 2 |
| Illinois | $40.4 | $40.4 | $39.03 - $41.77 | 4 |
| Michigan | $38.78 | $38.78 | $37.87 - $39.69 | 2 |
| North Carolina | $36.69 | $36.69 | $36.69 - $36.69 | 1 |
| New York | $41.15 | $41.15 | $36.97 - $43.43 | 5 |
| Ohio | $37.55 | $37.55 | $37.55 - $37.55 | 1 |
| Pennsylvania | $38.39 | $38.39 | $37.41 - $39.38 | 2 |
| Texas | $37.95 | $37.95 | $37.32 - $39.27 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 38207
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 38207 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 0538T | Column 1 (primary), can be billed with modifier | No | Mutually exclusive procedures |
| 36000 | Column 1 (primary), can be billed with modifier | 9 | Standards of medical/surgical practice |
| 36410 | Column 1 (primary), can be billed with modifier | 9 | Standards of medical/surgical practice |
| 36591 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 36592 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 37202 | Column 1 (primary), can be billed with modifier | 9 | Misuse of Column Two code with Column One code |
| 38226 | Column 1 (primary), can be billed with modifier | No | Mutually exclusive procedures |
| 62318 | Column 1 (primary), can be billed with modifier | 9 | Misuse of Column Two code with Column One code |
| 62319 | Column 1 (primary), can be billed with modifier | 9 | Misuse of Column Two code with Column One code |
| 64415 | Column 1 (primary), can be billed with modifier | 9 | Misuse of Column Two code with Column One code |
Frequently Asked Questions, CPT 38207
What does CPT code 38207 mean? +
CPT code 38207 represents: Cryopreserve stem cells. It's in the Surgery (Respiratory/Cardiovascular) category with a global period of XXX.
What is the Medicare reimbursement for CPT 38207? +
The 2026 Medicare national average non-facility payment for CPT 38207 is $38.56. Rates range from $35.89 to $51.82 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 38207? +
Surgery codes commonly use modifier 22 (increased procedural services), 50 (bilateral), 51 (multiple procedures), 52 (reduced services), 58/78/79 (staged, unplanned return, unrelated within global), 62 (co-surgeons), 80/82 (assistant surgeon), and 59 or the X{EPSU} subset for distinct procedural service.
What bundling edits apply to CPT 38207? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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