CPT 38205
Global 000Harvest allogeneic stem cell
CPT 38205 Billing & Documentation Guide
CPT code 38205 (Harvest allogeneic stem cell) is classified under Surgery (Respiratory/Cardiovascular) with a global period indicator of 000. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 1.46, a non-facility practice expense RVU of 0.52, and a malpractice RVU of 0.08, a total non-facility RVU of 2.06 and facility RVU of 2.06. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $70.18, though rates vary from $65.06 to $93.12 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 38205, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 38205 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Restricted coverage (special situations)
Endoscopic or minor procedure with related preoperative and postoperative work performed on the same day
MUE Limit (Medically Unlikely Edits)
Submitting more than 1 units of 38205 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 38205
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 1.46 | 1.46 |
| Practice Expense RVU | 0.52 | 0.52 |
| Malpractice RVU | 0.08 | 0.08 |
| Total RVU | 2.06 | 2.06 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 38205
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $72.51 | $72.51 | $70.06 - $80.61 | 29 |
| Florida | $71.39 | $71.39 | $69.39 - $73.6 | 3 |
| Georgia | $68.6 | $68.6 | $67.44 - $69.77 | 2 |
| Illinois | $70.83 | $70.83 | $68.8 - $72.69 | 4 |
| Michigan | $68.84 | $68.84 | $67.64 - $70.03 | 2 |
| North Carolina | $66.68 | $66.68 | $66.68 - $66.68 | 1 |
| New York | $74.09 | $74.09 | $67.14 - $77.5 | 5 |
| Ohio | $67.32 | $67.32 | $67.32 - $67.32 | 1 |
| Pennsylvania | $69.07 | $69.07 | $67.23 - $70.91 | 2 |
| Texas | $68.62 | $68.62 | $67.05 - $70.08 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 38205
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 38205 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 0213T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
| 0216T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
| 0228T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0230T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0537T | Column 1 (primary), can be billed with modifier | No | Mutually exclusive procedures |
| 0540T | Column 1 (primary), can be billed with modifier | No | Mutually exclusive procedures |
| 0596T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0597T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0708T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0709T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
Frequently Asked Questions, CPT 38205
What does CPT code 38205 mean? +
CPT code 38205 represents: Harvest allogeneic stem cell. It's in the Surgery (Respiratory/Cardiovascular) category with a global period of 000.
What is the Medicare reimbursement for CPT 38205? +
The 2026 Medicare national average non-facility payment for CPT 38205 is $70.18. Rates range from $65.06 to $93.12 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 38205? +
Surgery codes commonly use modifier 22 (increased procedural services), 50 (bilateral), 51 (multiple procedures), 52 (reduced services), 58/78/79 (staged, unplanned return, unrelated within global), 62 (co-surgeons), 80/82 (assistant surgeon), and 59 or the X{EPSU} subset for distinct procedural service.
What bundling edits apply to CPT 38205? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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