ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 Z48.280

Billable / Specific CC

Encounter for aftercare following heart-lung transplant

Z48
Block
0
Synonyms
553
LCDs
33
Payer Policies
4
Linked CPTs

About ICD-10-CM Z48.280

ICD-10-CM code Z48.280 represents Encounter for aftercare following heart-lung transplant. This is a billable/specific code in the Factors Influencing Health Status chapter (block Z48). The 2026 edition of ICD-10-CM Z48.280 became effective on October 1, 2025.

Coding Tips for Z48.280

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Inpatient DRG impact: CC

Z48.280 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Inpatient DRG Impact, CC

codes Encounter for aftercare following heart-lung transplant. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for Z48.280

Local Coverage Determinations (LCDs) from CMS MACs that list Z48.280 as a covered diagnosis.

553 LCDs

Showing top 10 of 553 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94660 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94726 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94664 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94618 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94772 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94642 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT G0238 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94004 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94668 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94680 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing Z48.280.

33 policies

2 Cigna

Transthoracic Echocardiography in Adults - (0510)
Policy ID: MM_0510
Transthoracic Echocardiography in Children - (0523)
Policy ID: MM_0523

5 Medicare

Immunosuppressive Drugs - Policy Article
Policy ID: ART-52474
Billing and Coding: Cardiac Catheterization and Coronary Angiography
Policy ID: ART-52850
Billing and Coding: Transesophageal Echocardiography (TEE)
Policy ID: ART-52868
Billing and Coding: Frequency and Duration for Cardiac Rehabilitation and Intensive Cardiac Rehabilitation
Policy ID: ART-53775
Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-55717

CPT Codes Commonly Billed with Z48.280

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

4 linkages
  • 93798 CMS LCD: Billing and Coding: Frequency and Duration for Cardiac Rehabilitation and Intensive Cardiac Rehabilitation CMS LCD
  • 93797 CMS LCD: Billing and Coding: Frequency and Duration for Cardiac Rehabilitation and Intensive Cardiac Rehabilitation CMS LCD
  • G0423 CMS LCD: Billing and Coding: Frequency and Duration for Cardiac Rehabilitation and Intensive Cardiac Rehabilitation CMS LCD
  • G0422 CMS LCD: Billing and Coding: Frequency and Duration for Cardiac Rehabilitation and Intensive Cardiac Rehabilitation CMS LCD

Convert Z48.280 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
Z48.280 V421 10112
Z48.280 V426 10113
Z48.280 V5844 10111

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

Codes Adjacent To Z48.280

Other codes in section Z40-Z53 (Encounters for other specific health care).

ICD-10 Z48.280, Billing FAQ

Is ICD-10 code Z48.280 billable? +

Yes, Z48.280 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Is Z48.280 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with Z48.280? +

Procedures frequently paired with Z48.280 include: 93798, 93797, G0423, G0422.

What ICD-9 codes does Z48.280 map to? +

Per CMS GEMs, Z48.280 maps to ICD-9 codes: V421, V426, V5844. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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