ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 T48.6

Non-Billable Header

Poisoning by, adverse effect of and underdosing of antiasthmatics, not elsewhere classified

T48
Block
1
Synonyms
0
LCDs
0
Payer Policies
0
Linked CPTs

About ICD-10-CM T48.6

ICD-10-CM code T48.6 represents Poisoning by, adverse effect of and underdosing of antiasthmatics, not elsewhere classified. This is a non-billable header code in the Injury, Poisoning, and External Causes chapter (block T48). The 2026 edition of ICD-10-CM T48.6 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.

Coding Tips for T48.6

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Injury chapter (S00-T88): 7th character extension required

Injury codes require a 7th character: A (initial encounter, active treatment), D (subsequent, healing/recovery), S (sequela, late effect of original injury). Codes with fewer than 6 characters need the placeholder X to bring them to 6 characters before adding the 7th. Wrong or missing 7th character is the #1 cause of injury claim denials.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under T48.6. Per CMS ICD-10-CM Tabular 2026.

  • Poisoning by, adverse effect of and underdosing of beta-adrenoreceptor agonists used in asthma therapy

Type 1 Excludes

Pure excludes, these codes can never be coded together with T48.6. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • poisoning by, adverse effect of and underdosing of beta-adrenoreceptor agonists not used in asthma therapy (T44.5)
  • poisoning by, adverse effect of and underdosing of anterior pituitary [adenohypophyseal] hormones (T38.8)

Medicare LCD Coverage for T48.6

Local Coverage Determinations (LCDs) from CMS MACs that list T48.6 as a covered diagnosis.

No Medicare LCDs reference T48.6 as covered

This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.

Commercial Payer Coverage

Coverage policies from major commercial payers referencing T48.6.

No commercial payer policies reference T48.6 on file

Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but T48.6 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.

CPT Codes Commonly Billed with T48.6

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for T48.6

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Codes Adjacent To T48.6

Other codes in section T36-T50 (Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances).

T36 Poisoning by, adverse effect of and underdosing of systemic antibiotics (non-billable) T36.0 Poisoning by, adverse effect of and underdosing of penicillins (non-billable) T36.0X Poisoning by, adverse effect of and underdosing of penicillins (non-billable) T36.0X1 Poisoning by penicillins, accidental (unintentional) (non-billable) T36.0X2 Poisoning by penicillins, intentional self-harm (non-billable) T36.0X3 Poisoning by penicillins, assault (non-billable) T36.0X4 Poisoning by penicillins, undetermined (non-billable) T36.0X5 Adverse effect of penicillins (non-billable) T36.0X6 Underdosing of penicillins (non-billable) T36.1 Poisoning by, adverse effect of and underdosing of cephalosporins and other beta-lactam antibiotics (non-billable) T36.1X Poisoning by, adverse effect of and underdosing of cephalosporins and other beta-lactam antibiotics (non-billable) T36.1X1 Poisoning by cephalosporins and other beta-lactam antibiotics, accidental (unintentional) (non-billable) T36.1X2 Poisoning by cephalosporins and other beta-lactam antibiotics, intentional self-harm (non-billable) T36.1X3 Poisoning by cephalosporins and other beta-lactam antibiotics, assault (non-billable) T36.1X4 Poisoning by cephalosporins and other beta-lactam antibiotics, undetermined (non-billable) T36.1X5 Adverse effect of cephalosporins and other beta-lactam antibiotics (non-billable) T36.1X6 Underdosing of cephalosporins and other beta-lactam antibiotics (non-billable) T36.2 Poisoning by, adverse effect of and underdosing of chloramphenicol group (non-billable) T36.2X Poisoning by, adverse effect of and underdosing of chloramphenicol group (non-billable) T36.2X1 Poisoning by chloramphenicol group, accidental (unintentional) (non-billable)

ICD-10 T48.6, Billing FAQ

Is ICD-10 code T48.6 billable? +

No, T48.6 is a non-billable header code. Use a more specific child code from block T48 when submitting claims.

What other names or terms map to T48.6? +

ICD-10 T48.6 includes: Poisoning by, adverse effect of and underdosing of beta-adrenoreceptor agonists used in asthma therapy.

What codes are Type 1 Excludes for T48.6? +

Type 1 Excludes (never code together with T48.6): poisoning by, adverse effect of and underdosing of beta-adrenoreceptor agonists not used in asthma therapy (T44.5); poisoning by, adverse effect of and underdosing of anterior pituitary [adenohypophyseal] hormones (T38.8)

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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